<italic toggle="yes">Caenorhabditis elegans</italic> RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs

<italic toggle="yes">Caenorhabditis elegans</italic> RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs

ABSTRACT Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals. Antiviral RNAi in Caenorhabditis elegans requires Dicer-relate...

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Bibliographic Details
Main Authors: Stephanie R. Coffman, Jinfeng Lu, Xunyang Guo, Jing Zhong, Hongshan Jiang, Gina Broitman-Maduro, Wan-Xiang Li, Rui Lu, Morris Maduro, Shou-wei Ding
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Caenorhabditis elegans
DRH-1
RNA interference
antiviral defense
Microbiology
QR1-502
Online Access:https://doaj.org/article/45ffc08346214478b128b610f1a9269b
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