HiCancer: accurate and complete cancer genome phasing with Hi-C reads

Abstract Due to the high complexity of cancer genome, it is too difficult to generate complete cancer genome map which contains the sequence of every DNA molecule until now. Nevertheless, phasing each chromosome in cancer genome into two haplotypes according to germline mutations provides a suboptim...

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Auteurs principaux: Weihua Pan, Desheng Gong, Da Sun, Haohui Luo
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/460b0ebe7f5446b4a76b9c5335960bcc
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