Association between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)

BACKGROUND AND OBJECTIVE: Recent studies were reported that H. Pylori infection and gastric atrophy were associated with an increased risk for esophageal squamous cell carcinoma (ESCC). However this finding needs to be confirmed in other ethnic group due to the wide geographic variation of this canc...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	J Shokry-Shirvany, A Jafari, E Shafigh, S Siadati, B Heidari, A Bijani, A Ghorbani
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2012
Materias:	helicobacter pylori esophageal squamous cell carcinoma gastric atrophy Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/460eebcc0ed04b22b469271d98b45b07
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:460eebcc0ed04b22b469271d98b45b07
record_format	dspace
spelling	oai:doaj.org-article:460eebcc0ed04b22b469271d98b45b072021-11-10T08:52:02ZAssociation between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)1561-41072251-7170https://doaj.org/article/460eebcc0ed04b22b469271d98b45b072012-01-01T00:00:00Zhttp://jbums.org/article-1-3988-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Recent studies were reported that H. Pylori infection and gastric atrophy were associated with an increased risk for esophageal squamous cell carcinoma (ESCC). However this finding needs to be confirmed in other ethnic group due to the wide geographic variation of this cancer. This case-control study was designed to evaluate the association between H. Pylori infection and gastric atrophy and ESCC.METHODS: In this case-control study, 33 patients suspected with ESCC who underwent upper gastrointestinal endoscopy and confirmed by histology, and 33 sex-and age-matched controls were enrolled. Gastric atrophy and H. Pylori infection were evaluated by histology of biopsy specimens. The association between two groups was compared.FINDINGS: Twenty (60.6%) patients in case group and 8 (24.2%) in control group were infected with H. Pylori. Severe H. Pylori infection defined histologically was associated with an increased risk of ESCC (p=0.035). There was no association between gastric atrophy and ESCC in our study.CONCLUSION: Our study showed a significant relationship between H. Pylori infections and ESCC. Further studies are warranted to explore the causal relationship.J Shokry-ShirvanyA JafariE ShafighS SiadatiB HeidariA BijaniA GhorbaniBabol University of Medical Sciencesarticlehelicobacter pyloriesophageal squamous cell carcinomagastric atrophyMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 14, Iss 1, Pp 13-18 (2012)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	helicobacter pylori esophageal squamous cell carcinoma gastric atrophy Medicine R Medicine (General) R5-920
spellingShingle	helicobacter pylori esophageal squamous cell carcinoma gastric atrophy Medicine R Medicine (General) R5-920 J Shokry-Shirvany A Jafari E Shafigh S Siadati B Heidari A Bijani A Ghorbani Association between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)
description	BACKGROUND AND OBJECTIVE: Recent studies were reported that H. Pylori infection and gastric atrophy were associated with an increased risk for esophageal squamous cell carcinoma (ESCC). However this finding needs to be confirmed in other ethnic group due to the wide geographic variation of this cancer. This case-control study was designed to evaluate the association between H. Pylori infection and gastric atrophy and ESCC.METHODS: In this case-control study, 33 patients suspected with ESCC who underwent upper gastrointestinal endoscopy and confirmed by histology, and 33 sex-and age-matched controls were enrolled. Gastric atrophy and H. Pylori infection were evaluated by histology of biopsy specimens. The association between two groups was compared.FINDINGS: Twenty (60.6%) patients in case group and 8 (24.2%) in control group were infected with H. Pylori. Severe H. Pylori infection defined histologically was associated with an increased risk of ESCC (p=0.035). There was no association between gastric atrophy and ESCC in our study.CONCLUSION: Our study showed a significant relationship between H. Pylori infections and ESCC. Further studies are warranted to explore the causal relationship.
format	article
author	J Shokry-Shirvany A Jafari E Shafigh S Siadati B Heidari A Bijani A Ghorbani
author_facet	J Shokry-Shirvany A Jafari E Shafigh S Siadati B Heidari A Bijani A Ghorbani
author_sort	J Shokry-Shirvany
title	Association between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)
title_short	Association between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)
title_full	Association between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)
title_fullStr	Association between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)
title_full_unstemmed	Association between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)
title_sort	association between helicobacter pylori (h. pylori) infection and esophageal squamus cell carcinoma (escc)
publisher	Babol University of Medical Sciences
publishDate	2012
url	https://doaj.org/article/460eebcc0ed04b22b469271d98b45b07
work_keys_str_mv	AT jshokryshirvany associationbetweenhelicobacterpylorihpyloriinfectionandesophagealsquamuscellcarcinomaescc AT ajafari associationbetweenhelicobacterpylorihpyloriinfectionandesophagealsquamuscellcarcinomaescc AT eshafigh associationbetweenhelicobacterpylorihpyloriinfectionandesophagealsquamuscellcarcinomaescc AT ssiadati associationbetweenhelicobacterpylorihpyloriinfectionandesophagealsquamuscellcarcinomaescc AT bheidari associationbetweenhelicobacterpylorihpyloriinfectionandesophagealsquamuscellcarcinomaescc AT abijani associationbetweenhelicobacterpylorihpyloriinfectionandesophagealsquamuscellcarcinomaescc AT aghorbani associationbetweenhelicobacterpylorihpyloriinfectionandesophagealsquamuscellcarcinomaescc
_version_	1718440367586541568

Association between Helicobacter Pylori (H. Pylori) Infection and Esophageal Squamus Cell Carcinoma (ESCC)

Ejemplares similares