DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data

Natalie Andersson et al. present DEVOLUTION, an algorithm and tool that allows researchers to reconstruct tumor clonal lineages from copy number and/or sequencing data. They validate this method on a diverse cohort of pediatric cancers, demonstrating its potential applications for cancer research.

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Detalles Bibliográficos
Autores principales: Natalie Andersson, Subhayan Chattopadhyay, Anders Valind, Jenny Karlsson, David Gisselsson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/46257a5e4a4247b2ac64a03a2839e78b
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Sumario:Natalie Andersson et al. present DEVOLUTION, an algorithm and tool that allows researchers to reconstruct tumor clonal lineages from copy number and/or sequencing data. They validate this method on a diverse cohort of pediatric cancers, demonstrating its potential applications for cancer research.