DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data

Natalie Andersson et al. present DEVOLUTION, an algorithm and tool that allows researchers to reconstruct tumor clonal lineages from copy number and/or sequencing data. They validate this method on a diverse cohort of pediatric cancers, demonstrating its potential applications for cancer research.

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Autores principales:	Natalie Andersson, Subhayan Chattopadhyay, Anders Valind, Jenny Karlsson, David Gisselsson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/46257a5e4a4247b2ac64a03a2839e78b
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spelling	oai:doaj.org-article:46257a5e4a4247b2ac64a03a2839e78b2021-12-02T18:14:07ZDEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data10.1038/s42003-021-02637-62399-3642https://doaj.org/article/46257a5e4a4247b2ac64a03a2839e78b2021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02637-6https://doaj.org/toc/2399-3642Natalie Andersson et al. present DEVOLUTION, an algorithm and tool that allows researchers to reconstruct tumor clonal lineages from copy number and/or sequencing data. They validate this method on a diverse cohort of pediatric cancers, demonstrating its potential applications for cancer research.Natalie AnderssonSubhayan ChattopadhyayAnders ValindJenny KarlssonDavid GisselssonNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Natalie Andersson Subhayan Chattopadhyay Anders Valind Jenny Karlsson David Gisselsson DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data
description	Natalie Andersson et al. present DEVOLUTION, an algorithm and tool that allows researchers to reconstruct tumor clonal lineages from copy number and/or sequencing data. They validate this method on a diverse cohort of pediatric cancers, demonstrating its potential applications for cancer research.
format	article
author	Natalie Andersson Subhayan Chattopadhyay Anders Valind Jenny Karlsson David Gisselsson
author_facet	Natalie Andersson Subhayan Chattopadhyay Anders Valind Jenny Karlsson David Gisselsson
author_sort	Natalie Andersson
title	DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data
title_short	DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data
title_full	DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data
title_fullStr	DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data
title_full_unstemmed	DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data
title_sort	devolution—a method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/46257a5e4a4247b2ac64a03a2839e78b
work_keys_str_mv	AT natalieandersson devolutionamethodforphylogeneticreconstructionofaneuploidcancersbasedonmultiregionalgenotypingdata AT subhayanchattopadhyay devolutionamethodforphylogeneticreconstructionofaneuploidcancersbasedonmultiregionalgenotypingdata AT andersvalind devolutionamethodforphylogeneticreconstructionofaneuploidcancersbasedonmultiregionalgenotypingdata AT jennykarlsson devolutionamethodforphylogeneticreconstructionofaneuploidcancersbasedonmultiregionalgenotypingdata AT davidgisselsson devolutionamethodforphylogeneticreconstructionofaneuploidcancersbasedonmultiregionalgenotypingdata
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DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data

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