The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion

Whilst estrogen is known to be tumorigenic in some breast cancer, in some contexts it can be protective against invasion and dissemination. Here, the authors show estrogen can promote generation of Suppressive Cortical Actin Bundles that can inhibit motility dynamics through EVL-mediated actin cytos...

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Autores principales:	Marco Padilla-Rodriguez, Sara S. Parker, Deanna G. Adams, Thomas Westerling, Julieann I. Puleo, Adam W. Watson, Samantha M. Hill, Muhammad Noon, Raphael Gaudin, Jesse Aaron, Daoqin Tong, Denise J. Roe, Beatrice Knudsen, Ghassan Mouneimne
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/46283693eda645978c7dcb8a878cd28b
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spelling	oai:doaj.org-article:46283693eda645978c7dcb8a878cd28b2021-12-02T13:27:23ZThe actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion10.1038/s41467-018-05367-22041-1723https://doaj.org/article/46283693eda645978c7dcb8a878cd28b2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05367-2https://doaj.org/toc/2041-1723Whilst estrogen is known to be tumorigenic in some breast cancer, in some contexts it can be protective against invasion and dissemination. Here, the authors show estrogen can promote generation of Suppressive Cortical Actin Bundles that can inhibit motility dynamics through EVL-mediated actin cytoskeletal remodeling.Marco Padilla-RodriguezSara S. ParkerDeanna G. AdamsThomas WesterlingJulieann I. PuleoAdam W. WatsonSamantha M. HillMuhammad NoonRaphael GaudinJesse AaronDaoqin TongDenise J. RoeBeatrice KnudsenGhassan MouneimneNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marco Padilla-Rodriguez Sara S. Parker Deanna G. Adams Thomas Westerling Julieann I. Puleo Adam W. Watson Samantha M. Hill Muhammad Noon Raphael Gaudin Jesse Aaron Daoqin Tong Denise J. Roe Beatrice Knudsen Ghassan Mouneimne The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion
description	Whilst estrogen is known to be tumorigenic in some breast cancer, in some contexts it can be protective against invasion and dissemination. Here, the authors show estrogen can promote generation of Suppressive Cortical Actin Bundles that can inhibit motility dynamics through EVL-mediated actin cytoskeletal remodeling.
format	article
author	Marco Padilla-Rodriguez Sara S. Parker Deanna G. Adams Thomas Westerling Julieann I. Puleo Adam W. Watson Samantha M. Hill Muhammad Noon Raphael Gaudin Jesse Aaron Daoqin Tong Denise J. Roe Beatrice Knudsen Ghassan Mouneimne
author_facet	Marco Padilla-Rodriguez Sara S. Parker Deanna G. Adams Thomas Westerling Julieann I. Puleo Adam W. Watson Samantha M. Hill Muhammad Noon Raphael Gaudin Jesse Aaron Daoqin Tong Denise J. Roe Beatrice Knudsen Ghassan Mouneimne
author_sort	Marco Padilla-Rodriguez
title	The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion
title_short	The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion
title_full	The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion
title_fullStr	The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion
title_full_unstemmed	The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion
title_sort	actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/46283693eda645978c7dcb8a878cd28b
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The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion

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