The nasal methylome as a biomarker of asthma and airway inflammation in children

Epigenetic differences in nasal epithelium have been proposed as a biomarker for lower airway disease and asthma. Here, in epigenome-wide association studies for asthma and other airway traits using nasal swabs, the authors identify differentially methylated CpGs that highlight genes involved in TH2...

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Main Authors: Andres Cardenas, Joanne E. Sordillo, Sheryl L. Rifas-Shiman, Wonil Chung, Liming Liang, Brent A. Coull, Marie-France Hivert, Peggy S. Lai, Erick Forno, Juan C. Celedón, Augusto A. Litonjua, Kasey J. Brennan, Dawn L. DeMeo, Andrea A. Baccarelli, Emily Oken, Diane R. Gold
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/463a3a6559c24a0d94c1e260b9956f71
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