Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII
Abstract Hemophilia A is an X-linked inherited blood coagulation disorder caused by the production and circulation of defective coagulation factor VIII protein. People living with this condition receive either prophylaxis or on-demand treatment, and approximately 30% of patients develop inhibitor an...
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Main Authors: | Tiago J. S. Lopes, Ricardo Rios, Tatiane Nogueira, Rodrigo F. Mello |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/463b9a2b09e6452aa5dfb631fb3f159b |
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