ROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY

Objective: To evaluate role of delayed phase tumor contrast washout in patients of hepatocellular carcinoma on computed tomography. Study Design: Comparative - cross-sectional study. Place and Duration of Study: Study was conducted in Department of Radiology, Pakistan Institute of Medical Scie...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ayesha Munir, Shahla Zameer
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	delayed phase hepatocellular carcinoma multiple detector computed tomography Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/463dc1902a1b4c79861803f075be487f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:463dc1902a1b4c79861803f075be487f
record_format	dspace
spelling	oai:doaj.org-article:463dc1902a1b4c79861803f075be487f2021-11-11T04:37:11ZROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY0030-96482411-8842https://doaj.org/article/463dc1902a1b4c79861803f075be487f2019-08-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3208/2317https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To evaluate role of delayed phase tumor contrast washout in patients of hepatocellular carcinoma on computed tomography. Study Design: Comparative - cross-sectional study. Place and Duration of Study: Study was conducted in Department of Radiology, Pakistan Institute of Medical Sciences and Islamabad, from Jan 2017 to Jul 2017. Material and Methods: A total of 54 patients with diagnosed HCCs on the basis of clinical, radiological and histopathological findings were included in the study. All the patients of HCC underwent Multiple detector computed tomography (MDCT) examination. A standard liver CT protocol was followed in all patients. All patients were given a non-ionic contrast medium having 350mg per ml concentration. The CT images were studied by two radiologists. Data was analyzed by SPSS version 20. Results: Total 79 hepatic cellular carcinomas were detected in 54 patients on MDCT on at least one imaging phase. The overall mean tumor size was 5.2 ± 1.79 cm, 64 (81%) were hypervascular and 15 (19%) were hypovascular. The subjective washout was found statistically significant (2=16.80, p-value=0.0001) for more tumors on delayed phase images (77.3% vs. 22.67%) as compared to hepatic venous phase images. The absolute value of mean tumor to liver contrast was significantly (p-value <0.05) higher on delayed phase images, (15 HU) in comparison to hepatic venous phase images (4 HU). Conclusion: On multiphasic MDCT the delayed phase has appreciably higher rate of detection of tumor washout in comparison to hepatic venous phase.Ayesha MunirShahla ZameerArmy Medical College Rawalpindiarticledelayed phasehepatocellular carcinomamultiple detector computed tomographyMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 4, Pp 826-830 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	delayed phase hepatocellular carcinoma multiple detector computed tomography Medicine R Medicine (General) R5-920
spellingShingle	delayed phase hepatocellular carcinoma multiple detector computed tomography Medicine R Medicine (General) R5-920 Ayesha Munir Shahla Zameer ROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY
description	Objective: To evaluate role of delayed phase tumor contrast washout in patients of hepatocellular carcinoma on computed tomography. Study Design: Comparative - cross-sectional study. Place and Duration of Study: Study was conducted in Department of Radiology, Pakistan Institute of Medical Sciences and Islamabad, from Jan 2017 to Jul 2017. Material and Methods: A total of 54 patients with diagnosed HCCs on the basis of clinical, radiological and histopathological findings were included in the study. All the patients of HCC underwent Multiple detector computed tomography (MDCT) examination. A standard liver CT protocol was followed in all patients. All patients were given a non-ionic contrast medium having 350mg per ml concentration. The CT images were studied by two radiologists. Data was analyzed by SPSS version 20. Results: Total 79 hepatic cellular carcinomas were detected in 54 patients on MDCT on at least one imaging phase. The overall mean tumor size was 5.2 ± 1.79 cm, 64 (81%) were hypervascular and 15 (19%) were hypovascular. The subjective washout was found statistically significant (2=16.80, p-value=0.0001) for more tumors on delayed phase images (77.3% vs. 22.67%) as compared to hepatic venous phase images. The absolute value of mean tumor to liver contrast was significantly (p-value <0.05) higher on delayed phase images, (15 HU) in comparison to hepatic venous phase images (4 HU). Conclusion: On multiphasic MDCT the delayed phase has appreciably higher rate of detection of tumor washout in comparison to hepatic venous phase.
format	article
author	Ayesha Munir Shahla Zameer
author_facet	Ayesha Munir Shahla Zameer
author_sort	Ayesha Munir
title	ROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY
title_short	ROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY
title_full	ROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY
title_fullStr	ROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY
title_full_unstemmed	ROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY
title_sort	role of delayed phase tumor contrast washout in patients of hepatocellular carcinoma on computed tomography
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/463dc1902a1b4c79861803f075be487f
work_keys_str_mv	AT ayeshamunir roleofdelayedphasetumorcontrastwashoutinpatientsofhepatocellularcarcinomaoncomputedtomography AT shahlazameer roleofdelayedphasetumorcontrastwashoutinpatientsofhepatocellularcarcinomaoncomputedtomography
_version_	1718439579922464768

ROLE OF DELAYED PHASE TUMOR CONTRAST WASHOUT IN PATIENTS OF HEPATOCELLULAR CARCINOMA ON COMPUTED TOMOGRAPHY

Ejemplares similares