ROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY

Objective: To assess the efficacy of perioperative analgesia with acetaminophen in reducing the occurrence and severity of post-ECT pain. Study Design: Quasi experimental study. Study Place and Duration: Tertiary care mental health facility at Rawalpindi, Jun to Nov 2018. Methodology: Patie...

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Autores principales:	Sana Khan, Rashid Qayyum, Khalid Buland, Mehwish Ujala, Usama Bin Zubair
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	electroconvulsive therapy headache myalgia perioperative analgesia Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/46400967e07840b9b7ab76137d7e7ce6
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spelling	oai:doaj.org-article:46400967e07840b9b7ab76137d7e7ce62021-11-08T05:18:53ZROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY0030-96482411-8842https://doaj.org/article/46400967e07840b9b7ab76137d7e7ce62019-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3392/2367https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess the efficacy of perioperative analgesia with acetaminophen in reducing the occurrence and severity of post-ECT pain. Study Design: Quasi experimental study. Study Place and Duration: Tertiary care mental health facility at Rawalpindi, Jun to Nov 2018. Methodology: Patients of all age groups and either gender for whom elective ECT was recommended during the study time period were included in the study. Acetaminophen (1g/100ml) and placebo (100ml) infusions were infused according to randomized sequence during ECT session. Study participants were assessed for presence and severity of pain i.e. headache and/or myalgia, two hours before and after ECT by using visual analog scale (VAS). Results: A sum of 146 study participants were randomized to either receive intervention (Group A) or placebo (Group B), both the groups comprised of 73 participants each. The frequency of post-ECT headache and myalgia in group A, who received acetaminophen infusion, was 8.2% and 2.7% respectively as compared to placebo group B where incidence of post-ECT headache and myalgia was reported to be 24.7% and 10.9% respectively (8.2% vs 24.7%, p 0.013 and 2.7% vs 10.9%, p 0.03 respectively). Uni-variate analysis showed that participants in group A were 72.6% less likely to develop post-ECT headache (OR 0.27, 95% CI 0.11-0.73, p 0.007), and 55% less likely to develop post-ECT myalgia (OR 0.45, 95% CI 0.21-0.80, p 0.01) than participants in group B. Conclusion: Acetaminophen has been found effective in reducing the incidence and severity of headache and myalgia following electroconvulsive therapy.Sana KhanRashid QayyumKhalid BulandMehwish UjalaUsama Bin ZubairArmy Medical College Rawalpindiarticleelectroconvulsive therapyheadachemyalgiaperioperative analgesiaMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 5, Pp 943-948 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	electroconvulsive therapy headache myalgia perioperative analgesia Medicine R Medicine (General) R5-920
spellingShingle	electroconvulsive therapy headache myalgia perioperative analgesia Medicine R Medicine (General) R5-920 Sana Khan Rashid Qayyum Khalid Buland Mehwish Ujala Usama Bin Zubair ROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY
description	Objective: To assess the efficacy of perioperative analgesia with acetaminophen in reducing the occurrence and severity of post-ECT pain. Study Design: Quasi experimental study. Study Place and Duration: Tertiary care mental health facility at Rawalpindi, Jun to Nov 2018. Methodology: Patients of all age groups and either gender for whom elective ECT was recommended during the study time period were included in the study. Acetaminophen (1g/100ml) and placebo (100ml) infusions were infused according to randomized sequence during ECT session. Study participants were assessed for presence and severity of pain i.e. headache and/or myalgia, two hours before and after ECT by using visual analog scale (VAS). Results: A sum of 146 study participants were randomized to either receive intervention (Group A) or placebo (Group B), both the groups comprised of 73 participants each. The frequency of post-ECT headache and myalgia in group A, who received acetaminophen infusion, was 8.2% and 2.7% respectively as compared to placebo group B where incidence of post-ECT headache and myalgia was reported to be 24.7% and 10.9% respectively (8.2% vs 24.7%, p 0.013 and 2.7% vs 10.9%, p 0.03 respectively). Uni-variate analysis showed that participants in group A were 72.6% less likely to develop post-ECT headache (OR 0.27, 95% CI 0.11-0.73, p 0.007), and 55% less likely to develop post-ECT myalgia (OR 0.45, 95% CI 0.21-0.80, p 0.01) than participants in group B. Conclusion: Acetaminophen has been found effective in reducing the incidence and severity of headache and myalgia following electroconvulsive therapy.
format	article
author	Sana Khan Rashid Qayyum Khalid Buland Mehwish Ujala Usama Bin Zubair
author_facet	Sana Khan Rashid Qayyum Khalid Buland Mehwish Ujala Usama Bin Zubair
author_sort	Sana Khan
title	ROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY
title_short	ROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY
title_full	ROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY
title_fullStr	ROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY
title_full_unstemmed	ROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY
title_sort	role of perioperative analgesia with acetaminophen in reducing pain following electroconvulsive therapy
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/46400967e07840b9b7ab76137d7e7ce6
work_keys_str_mv	AT sanakhan roleofperioperativeanalgesiawithacetaminopheninreducingpainfollowingelectroconvulsivetherapy AT rashidqayyum roleofperioperativeanalgesiawithacetaminopheninreducingpainfollowingelectroconvulsivetherapy AT khalidbuland roleofperioperativeanalgesiawithacetaminopheninreducingpainfollowingelectroconvulsivetherapy AT mehwishujala roleofperioperativeanalgesiawithacetaminopheninreducingpainfollowingelectroconvulsivetherapy AT usamabinzubair roleofperioperativeanalgesiawithacetaminopheninreducingpainfollowingelectroconvulsivetherapy
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ROLE OF PERIOPERATIVE ANALGESIA WITH ACETAMINOPHEN IN REDUCING PAIN FOLLOWING ELECTROCONVULSIVE THERAPY

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