Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
Highly metastatic dormant cancer cells contribute to breast cancer recurrence, but the underlying mechanism is less understood. Here, the authors show that dormant breast cancer cells depend on autophagy to ensure their long term survival and distant recurrence
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Nature Portfolio
2018
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oai:doaj.org-article:46452b335b2f42b194949651edfe435a2021-12-02T14:39:48ZAutophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence10.1038/s41467-018-04070-62041-1723https://doaj.org/article/46452b335b2f42b194949651edfe435a2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04070-6https://doaj.org/toc/2041-1723Highly metastatic dormant cancer cells contribute to breast cancer recurrence, but the underlying mechanism is less understood. Here, the authors show that dormant breast cancer cells depend on autophagy to ensure their long term survival and distant recurrenceLaura Vera-RamirezSuman K. VodnalaRyan NiniKent W. HunterJeffrey E. GreenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Laura Vera-Ramirez Suman K. Vodnala Ryan Nini Kent W. Hunter Jeffrey E. Green Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence |
description |
Highly metastatic dormant cancer cells contribute to breast cancer recurrence, but the underlying mechanism is less understood. Here, the authors show that dormant breast cancer cells depend on autophagy to ensure their long term survival and distant recurrence |
format |
article |
author |
Laura Vera-Ramirez Suman K. Vodnala Ryan Nini Kent W. Hunter Jeffrey E. Green |
author_facet |
Laura Vera-Ramirez Suman K. Vodnala Ryan Nini Kent W. Hunter Jeffrey E. Green |
author_sort |
Laura Vera-Ramirez |
title |
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence |
title_short |
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence |
title_full |
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence |
title_fullStr |
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence |
title_full_unstemmed |
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence |
title_sort |
autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/46452b335b2f42b194949651edfe435a |
work_keys_str_mv |
AT lauraveraramirez autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence AT sumankvodnala autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence AT ryannini autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence AT kentwhunter autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence AT jeffreyegreen autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence |
_version_ |
1718390469783715840 |