Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence

Highly metastatic dormant cancer cells contribute to breast cancer recurrence, but the underlying mechanism is less understood. Here, the authors show that dormant breast cancer cells depend on autophagy to ensure their long term survival and distant recurrence

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Autores principales: Laura Vera-Ramirez, Suman K. Vodnala, Ryan Nini, Kent W. Hunter, Jeffrey E. Green
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/46452b335b2f42b194949651edfe435a
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spelling oai:doaj.org-article:46452b335b2f42b194949651edfe435a2021-12-02T14:39:48ZAutophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence10.1038/s41467-018-04070-62041-1723https://doaj.org/article/46452b335b2f42b194949651edfe435a2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04070-6https://doaj.org/toc/2041-1723Highly metastatic dormant cancer cells contribute to breast cancer recurrence, but the underlying mechanism is less understood. Here, the authors show that dormant breast cancer cells depend on autophagy to ensure their long term survival and distant recurrenceLaura Vera-RamirezSuman K. VodnalaRyan NiniKent W. HunterJeffrey E. GreenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Laura Vera-Ramirez
Suman K. Vodnala
Ryan Nini
Kent W. Hunter
Jeffrey E. Green
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
description Highly metastatic dormant cancer cells contribute to breast cancer recurrence, but the underlying mechanism is less understood. Here, the authors show that dormant breast cancer cells depend on autophagy to ensure their long term survival and distant recurrence
format article
author Laura Vera-Ramirez
Suman K. Vodnala
Ryan Nini
Kent W. Hunter
Jeffrey E. Green
author_facet Laura Vera-Ramirez
Suman K. Vodnala
Ryan Nini
Kent W. Hunter
Jeffrey E. Green
author_sort Laura Vera-Ramirez
title Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
title_short Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
title_full Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
title_fullStr Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
title_full_unstemmed Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
title_sort autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/46452b335b2f42b194949651edfe435a
work_keys_str_mv AT lauraveraramirez autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence
AT sumankvodnala autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence
AT ryannini autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence
AT kentwhunter autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence
AT jeffreyegreen autophagypromotesthesurvivalofdormantbreastcancercellsandmetastatictumourrecurrence
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