TRIP6 functions in brain ciliogenesis

Cilia, tiny outgrowths of cells, are essential for life. Here, the author’s describe the scaffold protein TRIP6, which promotes the assembly of ciliary proteins required for ciliogenesis, and show that its absence results in hydrocephalus.

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Autores principales: Shalmali Shukla, Ronny Haenold, Pavel Urbánek, Lucien Frappart, Shamci Monajembashi, Paulius Grigaravicius, Sigrun Nagel, Woo Kee Min, Alicia Tapias, Olivier Kassel, Heike Heuer, Zhao-Qi Wang, Aspasia Ploubidou, Peter Herrlich
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4652349346cd445aaa9dd98d42752636
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spelling oai:doaj.org-article:4652349346cd445aaa9dd98d427526362021-12-02T19:16:33ZTRIP6 functions in brain ciliogenesis10.1038/s41467-021-26057-62041-1723https://doaj.org/article/4652349346cd445aaa9dd98d427526362021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26057-6https://doaj.org/toc/2041-1723Cilia, tiny outgrowths of cells, are essential for life. Here, the author’s describe the scaffold protein TRIP6, which promotes the assembly of ciliary proteins required for ciliogenesis, and show that its absence results in hydrocephalus.Shalmali ShuklaRonny HaenoldPavel UrbánekLucien FrappartShamci MonajembashiPaulius GrigaraviciusSigrun NagelWoo Kee MinAlicia TapiasOlivier KasselHeike HeuerZhao-Qi WangAspasia PloubidouPeter HerrlichNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shalmali Shukla
Ronny Haenold
Pavel Urbánek
Lucien Frappart
Shamci Monajembashi
Paulius Grigaravicius
Sigrun Nagel
Woo Kee Min
Alicia Tapias
Olivier Kassel
Heike Heuer
Zhao-Qi Wang
Aspasia Ploubidou
Peter Herrlich
TRIP6 functions in brain ciliogenesis
description Cilia, tiny outgrowths of cells, are essential for life. Here, the author’s describe the scaffold protein TRIP6, which promotes the assembly of ciliary proteins required for ciliogenesis, and show that its absence results in hydrocephalus.
format article
author Shalmali Shukla
Ronny Haenold
Pavel Urbánek
Lucien Frappart
Shamci Monajembashi
Paulius Grigaravicius
Sigrun Nagel
Woo Kee Min
Alicia Tapias
Olivier Kassel
Heike Heuer
Zhao-Qi Wang
Aspasia Ploubidou
Peter Herrlich
author_facet Shalmali Shukla
Ronny Haenold
Pavel Urbánek
Lucien Frappart
Shamci Monajembashi
Paulius Grigaravicius
Sigrun Nagel
Woo Kee Min
Alicia Tapias
Olivier Kassel
Heike Heuer
Zhao-Qi Wang
Aspasia Ploubidou
Peter Herrlich
author_sort Shalmali Shukla
title TRIP6 functions in brain ciliogenesis
title_short TRIP6 functions in brain ciliogenesis
title_full TRIP6 functions in brain ciliogenesis
title_fullStr TRIP6 functions in brain ciliogenesis
title_full_unstemmed TRIP6 functions in brain ciliogenesis
title_sort trip6 functions in brain ciliogenesis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4652349346cd445aaa9dd98d42752636
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