TRIP6 functions in brain ciliogenesis
Cilia, tiny outgrowths of cells, are essential for life. Here, the author’s describe the scaffold protein TRIP6, which promotes the assembly of ciliary proteins required for ciliogenesis, and show that its absence results in hydrocephalus.
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Nature Portfolio
2021
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oai:doaj.org-article:4652349346cd445aaa9dd98d427526362021-12-02T19:16:33ZTRIP6 functions in brain ciliogenesis10.1038/s41467-021-26057-62041-1723https://doaj.org/article/4652349346cd445aaa9dd98d427526362021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26057-6https://doaj.org/toc/2041-1723Cilia, tiny outgrowths of cells, are essential for life. Here, the author’s describe the scaffold protein TRIP6, which promotes the assembly of ciliary proteins required for ciliogenesis, and show that its absence results in hydrocephalus.Shalmali ShuklaRonny HaenoldPavel UrbánekLucien FrappartShamci MonajembashiPaulius GrigaraviciusSigrun NagelWoo Kee MinAlicia TapiasOlivier KasselHeike HeuerZhao-Qi WangAspasia PloubidouPeter HerrlichNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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EN |
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Science Q |
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Science Q Shalmali Shukla Ronny Haenold Pavel Urbánek Lucien Frappart Shamci Monajembashi Paulius Grigaravicius Sigrun Nagel Woo Kee Min Alicia Tapias Olivier Kassel Heike Heuer Zhao-Qi Wang Aspasia Ploubidou Peter Herrlich TRIP6 functions in brain ciliogenesis |
description |
Cilia, tiny outgrowths of cells, are essential for life. Here, the author’s describe the scaffold protein TRIP6, which promotes the assembly of ciliary proteins required for ciliogenesis, and show that its absence results in hydrocephalus. |
format |
article |
author |
Shalmali Shukla Ronny Haenold Pavel Urbánek Lucien Frappart Shamci Monajembashi Paulius Grigaravicius Sigrun Nagel Woo Kee Min Alicia Tapias Olivier Kassel Heike Heuer Zhao-Qi Wang Aspasia Ploubidou Peter Herrlich |
author_facet |
Shalmali Shukla Ronny Haenold Pavel Urbánek Lucien Frappart Shamci Monajembashi Paulius Grigaravicius Sigrun Nagel Woo Kee Min Alicia Tapias Olivier Kassel Heike Heuer Zhao-Qi Wang Aspasia Ploubidou Peter Herrlich |
author_sort |
Shalmali Shukla |
title |
TRIP6 functions in brain ciliogenesis |
title_short |
TRIP6 functions in brain ciliogenesis |
title_full |
TRIP6 functions in brain ciliogenesis |
title_fullStr |
TRIP6 functions in brain ciliogenesis |
title_full_unstemmed |
TRIP6 functions in brain ciliogenesis |
title_sort |
trip6 functions in brain ciliogenesis |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/4652349346cd445aaa9dd98d42752636 |
work_keys_str_mv |
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