Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer

The clonal architecture of colon cancer and the relevance of tumor cell subpopulations for clonal outgrowth are poorly understood. Here, the authors describe the clonal architecture and dynamics in human colon cancer by using a multicolor lineage tracing approach in colon cancer xenografts.

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Autores principales:	Sebastian Lamprecht, Eva Marina Schmidt, Cristina Blaj, Heiko Hermeking, Andreas Jung, Thomas Kirchner, David Horst
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/465bc578e97e4dd48e8e328e7fe37634
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spelling	oai:doaj.org-article:465bc578e97e4dd48e8e328e7fe376342021-12-02T14:42:07ZMulticolor lineage tracing reveals clonal architecture and dynamics in colon cancer10.1038/s41467-017-00976-92041-1723https://doaj.org/article/465bc578e97e4dd48e8e328e7fe376342017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00976-9https://doaj.org/toc/2041-1723The clonal architecture of colon cancer and the relevance of tumor cell subpopulations for clonal outgrowth are poorly understood. Here, the authors describe the clonal architecture and dynamics in human colon cancer by using a multicolor lineage tracing approach in colon cancer xenografts.Sebastian LamprechtEva Marina SchmidtCristina BlajHeiko HermekingAndreas JungThomas KirchnerDavid HorstNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sebastian Lamprecht Eva Marina Schmidt Cristina Blaj Heiko Hermeking Andreas Jung Thomas Kirchner David Horst Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
description	The clonal architecture of colon cancer and the relevance of tumor cell subpopulations for clonal outgrowth are poorly understood. Here, the authors describe the clonal architecture and dynamics in human colon cancer by using a multicolor lineage tracing approach in colon cancer xenografts.
format	article
author	Sebastian Lamprecht Eva Marina Schmidt Cristina Blaj Heiko Hermeking Andreas Jung Thomas Kirchner David Horst
author_facet	Sebastian Lamprecht Eva Marina Schmidt Cristina Blaj Heiko Hermeking Andreas Jung Thomas Kirchner David Horst
author_sort	Sebastian Lamprecht
title	Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
title_short	Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
title_full	Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
title_fullStr	Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
title_full_unstemmed	Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
title_sort	multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/465bc578e97e4dd48e8e328e7fe37634
work_keys_str_mv	AT sebastianlamprecht multicolorlineagetracingrevealsclonalarchitectureanddynamicsincoloncancer AT evamarinaschmidt multicolorlineagetracingrevealsclonalarchitectureanddynamicsincoloncancer AT cristinablaj multicolorlineagetracingrevealsclonalarchitectureanddynamicsincoloncancer AT heikohermeking multicolorlineagetracingrevealsclonalarchitectureanddynamicsincoloncancer AT andreasjung multicolorlineagetracingrevealsclonalarchitectureanddynamicsincoloncancer AT thomaskirchner multicolorlineagetracingrevealsclonalarchitectureanddynamicsincoloncancer AT davidhorst multicolorlineagetracingrevealsclonalarchitectureanddynamicsincoloncancer
_version_	1718389805006454784

Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer

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