ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES

Hyperglycemia and dyslipidemia are common metabolic abnormalities in adults with type 1 diabetes mellitus (T1DM) and both increase cardiovascular disease risk. Normalization of lipid metabolism is a mandatory element in prevention of diabetic micro- and macroangiopathies in patients with T1DM and it...

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Auteurs principaux:	V. S. Syomshchikov, L. Y. Khamnueva, E. V. Chugunova
Format:	article
Langue:	RU
Publié:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Sujets:	diabetes mellitus dyslipidemia cholesterol hdl ldl vldl triglycerides non-hdl Science Q
Accès en ligne:	https://doaj.org/article/4679e0012c974d5f88f43be7cae8811b
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spelling	oai:doaj.org-article:4679e0012c974d5f88f43be7cae8811b2021-11-23T06:14:36ZABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES2541-94202587-959610.12737/23790https://doaj.org/article/4679e0012c974d5f88f43be7cae8811b2016-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/331https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Hyperglycemia and dyslipidemia are common metabolic abnormalities in adults with type 1 diabetes mellitus (T1DM) and both increase cardiovascular disease risk. Normalization of lipid metabolism is a mandatory element in prevention of diabetic micro- and macroangiopathies in patients with T1DM and it is directly related to improvement of health outcome. We aimed to investigate serum lipid profiles in patients with T1DM and poor glycemic control. Among observed patients with T1DM, 76 % were classified as having dyslipidemia, dyslipidemia rate was higher in patients with diabetic microangiopathies. Patients with T1DM and microvascular complications, arterial hypertension (AH) and the level of glycated hemoglobin (HbA1c) > 8 % had significantly higher levels of total cholesterol (TC), very low density lipoproteins (VLDL), triglycerides (TG) and non-high density lipoproteins (non-HDL). Therefore, management of patients with T1DM at the outpatient stage requires a strict control of lipid metabolism.V. S. SyomshchikovL. Y. KhamnuevaE. V. ChugunovaScientific Сentre for Family Health and Human Reproduction Problemsarticlediabetes mellitusdyslipidemiacholesterolhdlldlvldltriglyceridesnon-hdlScienceQRUActa Biomedica Scientifica, Vol 1, Iss 6, Pp 113-117 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	diabetes mellitus dyslipidemia cholesterol hdl ldl vldl triglycerides non-hdl Science Q
spellingShingle	diabetes mellitus dyslipidemia cholesterol hdl ldl vldl triglycerides non-hdl Science Q V. S. Syomshchikov L. Y. Khamnueva E. V. Chugunova ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES
description	Hyperglycemia and dyslipidemia are common metabolic abnormalities in adults with type 1 diabetes mellitus (T1DM) and both increase cardiovascular disease risk. Normalization of lipid metabolism is a mandatory element in prevention of diabetic micro- and macroangiopathies in patients with T1DM and it is directly related to improvement of health outcome. We aimed to investigate serum lipid profiles in patients with T1DM and poor glycemic control. Among observed patients with T1DM, 76 % were classified as having dyslipidemia, dyslipidemia rate was higher in patients with diabetic microangiopathies. Patients with T1DM and microvascular complications, arterial hypertension (AH) and the level of glycated hemoglobin (HbA1c) > 8 % had significantly higher levels of total cholesterol (TC), very low density lipoproteins (VLDL), triglycerides (TG) and non-high density lipoproteins (non-HDL). Therefore, management of patients with T1DM at the outpatient stage requires a strict control of lipid metabolism.
format	article
author	V. S. Syomshchikov L. Y. Khamnueva E. V. Chugunova
author_facet	V. S. Syomshchikov L. Y. Khamnueva E. V. Chugunova
author_sort	V. S. Syomshchikov
title	ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES
title_short	ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES
title_full	ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES
title_fullStr	ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES
title_full_unstemmed	ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES
title_sort	abnormality of lipid metabolism in patients with diabetes mellitus type 1 and poor glycemic control with and without diabetic microangiopathies
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/4679e0012c974d5f88f43be7cae8811b
work_keys_str_mv	AT vssyomshchikov abnormalityoflipidmetabolisminpatientswithdiabetesmellitustype1andpoorglycemiccontrolwithandwithoutdiabeticmicroangiopathies AT lykhamnueva abnormalityoflipidmetabolisminpatientswithdiabetesmellitustype1andpoorglycemiccontrolwithandwithoutdiabeticmicroangiopathies AT evchugunova abnormalityoflipidmetabolisminpatientswithdiabetesmellitustype1andpoorglycemiccontrolwithandwithoutdiabeticmicroangiopathies
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ABNORMALITY OF LIPID METABOLISM IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND POOR GLYCEMIC CONTROL WITH AND WITHOUT DIABETIC MICROANGIOPATHIES

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