Genetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.

Sichuan, China, has abundant genetic resources of sheep (Ovis aries). However, their genetic diversity and population structure have been less studied, especially at the genome-wide level. In the present study, we employed the specific-locus amplified fragment sequencing for identifying genome-wide...

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Autores principales:	Mingliang Zhou, Gaofu Wang, Minghua Chen, Qian Pang, Shihai Jiang, Jie Zeng, Dan Du, Pinggui Yang, Weisheng Wu, Hongwen Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/467f27a6698246c99c330fba2c226994
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id	oai:doaj.org-article:467f27a6698246c99c330fba2c226994
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spelling	oai:doaj.org-article:467f27a6698246c99c330fba2c2269942021-12-02T20:17:27ZGenetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.1932-620310.1371/journal.pone.0257974https://doaj.org/article/467f27a6698246c99c330fba2c2269942021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0257974https://doaj.org/toc/1932-6203Sichuan, China, has abundant genetic resources of sheep (Ovis aries). However, their genetic diversity and population structure have been less studied, especially at the genome-wide level. In the present study, we employed the specific-locus amplified fragment sequencing for identifying genome-wide single nucleotide polymorphisms (SNPs) among five breeds of sheep distributed in Sichuan, including three local pure breeds, one composite breed, and one exotic breed of White Suffolk. From 494 million clean paired-end reads, we obtained a total of 327,845 high-quality SNPs that were evenly distributed among all 27 chromosomes, with a transition/transversion ratio of 2.56. Based on this SNP panel, we found that the overall nucleotide diversity was 0.2284 for all five breeds, with the highest and lowest diversity observed in Mage sheep (0.2125) and Butuo Black (0.1963) sheep, respectively. Both Wright's fixation index and Identity-by-State distance revealed that all individuals of Liangshan Semifine-wool, White Suffolk, and Butuo Black sheep were respectively clustered together, and the breeds could be separated from each other, whereas Jialuo and Mage sheep had the closest genetic relationship and could not be distinguished from each other. In conclusion, we provide a reference panel of genome-wide and high-quality SNPs in five sheep breeds in Sichuan, by which their genetic diversity and population structures were investigated.Mingliang ZhouGaofu WangMinghua ChenQian PangShihai JiangJie ZengDan DuPinggui YangWeisheng WuHongwen ZhaoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0257974 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mingliang Zhou Gaofu Wang Minghua Chen Qian Pang Shihai Jiang Jie Zeng Dan Du Pinggui Yang Weisheng Wu Hongwen Zhao Genetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.
description	Sichuan, China, has abundant genetic resources of sheep (Ovis aries). However, their genetic diversity and population structure have been less studied, especially at the genome-wide level. In the present study, we employed the specific-locus amplified fragment sequencing for identifying genome-wide single nucleotide polymorphisms (SNPs) among five breeds of sheep distributed in Sichuan, including three local pure breeds, one composite breed, and one exotic breed of White Suffolk. From 494 million clean paired-end reads, we obtained a total of 327,845 high-quality SNPs that were evenly distributed among all 27 chromosomes, with a transition/transversion ratio of 2.56. Based on this SNP panel, we found that the overall nucleotide diversity was 0.2284 for all five breeds, with the highest and lowest diversity observed in Mage sheep (0.2125) and Butuo Black (0.1963) sheep, respectively. Both Wright's fixation index and Identity-by-State distance revealed that all individuals of Liangshan Semifine-wool, White Suffolk, and Butuo Black sheep were respectively clustered together, and the breeds could be separated from each other, whereas Jialuo and Mage sheep had the closest genetic relationship and could not be distinguished from each other. In conclusion, we provide a reference panel of genome-wide and high-quality SNPs in five sheep breeds in Sichuan, by which their genetic diversity and population structures were investigated.
format	article
author	Mingliang Zhou Gaofu Wang Minghua Chen Qian Pang Shihai Jiang Jie Zeng Dan Du Pinggui Yang Weisheng Wu Hongwen Zhao
author_facet	Mingliang Zhou Gaofu Wang Minghua Chen Qian Pang Shihai Jiang Jie Zeng Dan Du Pinggui Yang Weisheng Wu Hongwen Zhao
author_sort	Mingliang Zhou
title	Genetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.
title_short	Genetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.
title_full	Genetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.
title_fullStr	Genetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.
title_full_unstemmed	Genetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.
title_sort	genetic diversity and population structure of sheep (ovis aries) in sichuan, china.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/467f27a6698246c99c330fba2c226994
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_version_	1718374341195857920

Genetic diversity and population structure of sheep (Ovis aries) in Sichuan, China.

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