Antihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea

Goitom Mebrahtu,1 Mary M Moleki,2 Oliver Okoth Achila,3 Yemane Seyoum,4 Elias T Adnoy,5 Martin Ovberedjo6 1Division of Clinical Services, Ministry of Health, Asmara, Eritrea; 2Department of Health Studies, University of South Africa (UNISA), Pretoria, South Africa; 3Department of Clinical Laboratory...

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Autores principales:	Mebrahtu G, M Moleki M, Okoth Achila O, Seyoum Y, Adnoy ET, Ovberedjo M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	eritrea knowledge hypertension medication adherence. Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/46810ea2e6294ab1923623ff19cbc7f3
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spelling	oai:doaj.org-article:46810ea2e6294ab1923623ff19cbc7f32021-11-23T18:43:01ZAntihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea1177-889Xhttps://doaj.org/article/46810ea2e6294ab1923623ff19cbc7f32021-11-01T00:00:00Zhttps://www.dovepress.com/antihypertensive-medication-adherence-and-associated-factors-a-cross-s-peer-reviewed-fulltext-article-PPAhttps://doaj.org/toc/1177-889XGoitom Mebrahtu,1 Mary M Moleki,2 Oliver Okoth Achila,3 Yemane Seyoum,4 Elias T Adnoy,5 Martin Ovberedjo6 1Division of Clinical Services, Ministry of Health, Asmara, Eritrea; 2Department of Health Studies, University of South Africa (UNISA), Pretoria, South Africa; 3Department of Clinical Laboratory Services, Orotta School of Medicine and Health Sciences, Asmara, Eritrea; 4Department of Internal Medicine, Orotta School of Medicine and Health Sciences, Asmara, Eritrea; 5Public Health Unit, Orotta School of Medicine and Health Science, Asmara, Eritrea; 6Eritrea Country Office, World Health Organisation (WHO), Asmara, EritreaCorrespondence: Oliver Okoth Achila Email oliverachila@gmail.comBackground: Recent research suggests that poor adherence to antihypertensive medication (AHM) is a major problem in the management of hypertension. This study was therefore designed to evaluate the frequency of AHM and associated risk factors in patients attending a national referral hospital in Asmara, Eritrea.Methods: A total of 335 respondents (females: 222 (66.3%) participated in this cross-sectional study. Adherence to Medication was evaluated using a modified version of the Medication Adherence Report Scale (MARS). Additional data were abstracted from patients’ medical records and a WHO STEPwise questionnaire.Results: The mean (±SD) age of the study participants was 59.65 (± 12.20) years (females: 56.82 (± 9.95) vs males: 57.17 (± 9.60) years, p-value=0.001). Similarly, the median (IQR) for diastolic blood pressure (DBP) and systolic blood pressure (SBP) were 85.00 mmHg (IQR: 80.00– 90.00 mmHg) and 145.00 mmHg (IQR: 130.00– 160.00 mmHg), respectively. Overall, 246 (73.4%) and 244 (72.8%) participants had poor knowledge and poor adherence to AHM, respectively. In the multivariate analysis, factors associated with increased odds of poor adherence to AHM included sex (females: adjusted odds ratio (aOR): 4.95; 95% CI: 1.52– 16.11, p value=0.008); employment status (Ref: employed/NGO) (self-employed: aOR: 1.95; 95% CI: 0.45– 8.48, p-value=0.373) (housewife: aOR: 0.13; 95% CI: 0.04– 0.413, p-value=0.001) (unemployed: aOR: 1.38; 95% CI:0.32– 5.98; p-value=0.670); lack of attendance of health talk at the clinic (aOR: 2.33; 95% CI: 1.17– 4.63; p-value=0.016); high cost of transportation (yes: aOR: 6.87; 95% CI: 3.25– 14.52; p-value< 0.001); knowledge (poor: aOR: 6.23; 95% CI: 2.36– 18.05, p-value< 0.001) and hypertension stage (Stage 3: aOR: 5.55; 95% CI, 1.44– 21.37, p-value=0.013). Low level of knowledge regarding hypertension-related complications or associated risk factors was also noted.Conclusion: The high level of poor adherence to anti-hypertension medications and low level of knowledge on hypertension should raise concern. Overall, decentralization of health care services and educational support are vital intervention pathways in this population.Keywords: Eritrea, knowledge, hypertension, medication adherenceMebrahtu GM Moleki MOkoth Achila OSeyoum YAdnoy ETOvberedjo MDove Medical Pressarticleeritreaknowledgehypertensionmedication adherence.Medicine (General)R5-920ENPatient Preference and Adherence, Vol Volume 15, Pp 2619-2632 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	eritrea knowledge hypertension medication adherence. Medicine (General) R5-920
spellingShingle	eritrea knowledge hypertension medication adherence. Medicine (General) R5-920 Mebrahtu G M Moleki M Okoth Achila O Seyoum Y Adnoy ET Ovberedjo M Antihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea
description	Goitom Mebrahtu,1 Mary M Moleki,2 Oliver Okoth Achila,3 Yemane Seyoum,4 Elias T Adnoy,5 Martin Ovberedjo6 1Division of Clinical Services, Ministry of Health, Asmara, Eritrea; 2Department of Health Studies, University of South Africa (UNISA), Pretoria, South Africa; 3Department of Clinical Laboratory Services, Orotta School of Medicine and Health Sciences, Asmara, Eritrea; 4Department of Internal Medicine, Orotta School of Medicine and Health Sciences, Asmara, Eritrea; 5Public Health Unit, Orotta School of Medicine and Health Science, Asmara, Eritrea; 6Eritrea Country Office, World Health Organisation (WHO), Asmara, EritreaCorrespondence: Oliver Okoth Achila Email oliverachila@gmail.comBackground: Recent research suggests that poor adherence to antihypertensive medication (AHM) is a major problem in the management of hypertension. This study was therefore designed to evaluate the frequency of AHM and associated risk factors in patients attending a national referral hospital in Asmara, Eritrea.Methods: A total of 335 respondents (females: 222 (66.3%) participated in this cross-sectional study. Adherence to Medication was evaluated using a modified version of the Medication Adherence Report Scale (MARS). Additional data were abstracted from patients’ medical records and a WHO STEPwise questionnaire.Results: The mean (±SD) age of the study participants was 59.65 (± 12.20) years (females: 56.82 (± 9.95) vs males: 57.17 (± 9.60) years, p-value=0.001). Similarly, the median (IQR) for diastolic blood pressure (DBP) and systolic blood pressure (SBP) were 85.00 mmHg (IQR: 80.00– 90.00 mmHg) and 145.00 mmHg (IQR: 130.00– 160.00 mmHg), respectively. Overall, 246 (73.4%) and 244 (72.8%) participants had poor knowledge and poor adherence to AHM, respectively. In the multivariate analysis, factors associated with increased odds of poor adherence to AHM included sex (females: adjusted odds ratio (aOR): 4.95; 95% CI: 1.52– 16.11, p value=0.008); employment status (Ref: employed/NGO) (self-employed: aOR: 1.95; 95% CI: 0.45– 8.48, p-value=0.373) (housewife: aOR: 0.13; 95% CI: 0.04– 0.413, p-value=0.001) (unemployed: aOR: 1.38; 95% CI:0.32– 5.98; p-value=0.670); lack of attendance of health talk at the clinic (aOR: 2.33; 95% CI: 1.17– 4.63; p-value=0.016); high cost of transportation (yes: aOR: 6.87; 95% CI: 3.25– 14.52; p-value< 0.001); knowledge (poor: aOR: 6.23; 95% CI: 2.36– 18.05, p-value< 0.001) and hypertension stage (Stage 3: aOR: 5.55; 95% CI, 1.44– 21.37, p-value=0.013). Low level of knowledge regarding hypertension-related complications or associated risk factors was also noted.Conclusion: The high level of poor adherence to anti-hypertension medications and low level of knowledge on hypertension should raise concern. Overall, decentralization of health care services and educational support are vital intervention pathways in this population.Keywords: Eritrea, knowledge, hypertension, medication adherence
format	article
author	Mebrahtu G M Moleki M Okoth Achila O Seyoum Y Adnoy ET Ovberedjo M
author_facet	Mebrahtu G M Moleki M Okoth Achila O Seyoum Y Adnoy ET Ovberedjo M
author_sort	Mebrahtu G
title	Antihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea
title_short	Antihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea
title_full	Antihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea
title_fullStr	Antihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea
title_full_unstemmed	Antihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea
title_sort	antihypertensive medication adherence and associated factors: a cross-sectional analysis of patients attending a national referral hospital in asmara, eritrea
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/46810ea2e6294ab1923623ff19cbc7f3
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Antihypertensive Medication Adherence and Associated Factors: A Cross-Sectional Analysis of Patients Attending a National Referral Hospital in Asmara, Eritrea

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