Modeling the impact of drug interactions on therapeutic selectivity
While drugs can interact in both target and off-target cell types, more favorable interaction in the target cell may nevertheless allow for a therapeutic window. Here, the authors show, using two yeast species as a model, that differential drug interactions indeed adjust the selective window.
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/469370dc8ba0481e8780ba4f7a1c399a |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|