Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen

Studying emerging pathogens is often challenging due to the lack of information. Here the authors show that dual RNA-seq, profiling the host and pathogen transcriptome simultaneously, helps uncovering the biology of Orientia tsutsugamushi, a major cause of febrile illness in South-East Asia, and its...

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Autores principales:	Bozena Mika-Gospodorz, Suparat Giengkam, Alexander J. Westermann, Jantana Wongsantichon, Willow Kion-Crosby, Suthida Chuenklin, Loo Chien Wang, Piyanate Sunyakumthorn, Radoslaw M. Sobota, Selvakumar Subbian, Jörg Vogel, Lars Barquist, Jeanne Salje
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/46adddfa7d4548f68077abbc70f1fb90
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spelling	oai:doaj.org-article:46adddfa7d4548f68077abbc70f1fb902021-12-02T16:31:47ZDual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen10.1038/s41467-020-17094-82041-1723https://doaj.org/article/46adddfa7d4548f68077abbc70f1fb902020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17094-8https://doaj.org/toc/2041-1723Studying emerging pathogens is often challenging due to the lack of information. Here the authors show that dual RNA-seq, profiling the host and pathogen transcriptome simultaneously, helps uncovering the biology of Orientia tsutsugamushi, a major cause of febrile illness in South-East Asia, and its interaction with the host.Bozena Mika-GospodorzSuparat GiengkamAlexander J. WestermannJantana WongsantichonWillow Kion-CrosbySuthida ChuenklinLoo Chien WangPiyanate SunyakumthornRadoslaw M. SobotaSelvakumar SubbianJörg VogelLars BarquistJeanne SaljeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bozena Mika-Gospodorz Suparat Giengkam Alexander J. Westermann Jantana Wongsantichon Willow Kion-Crosby Suthida Chuenklin Loo Chien Wang Piyanate Sunyakumthorn Radoslaw M. Sobota Selvakumar Subbian Jörg Vogel Lars Barquist Jeanne Salje Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
description	Studying emerging pathogens is often challenging due to the lack of information. Here the authors show that dual RNA-seq, profiling the host and pathogen transcriptome simultaneously, helps uncovering the biology of Orientia tsutsugamushi, a major cause of febrile illness in South-East Asia, and its interaction with the host.
format	article
author	Bozena Mika-Gospodorz Suparat Giengkam Alexander J. Westermann Jantana Wongsantichon Willow Kion-Crosby Suthida Chuenklin Loo Chien Wang Piyanate Sunyakumthorn Radoslaw M. Sobota Selvakumar Subbian Jörg Vogel Lars Barquist Jeanne Salje
author_facet	Bozena Mika-Gospodorz Suparat Giengkam Alexander J. Westermann Jantana Wongsantichon Willow Kion-Crosby Suthida Chuenklin Loo Chien Wang Piyanate Sunyakumthorn Radoslaw M. Sobota Selvakumar Subbian Jörg Vogel Lars Barquist Jeanne Salje
author_sort	Bozena Mika-Gospodorz
title	Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
title_short	Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
title_full	Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
title_fullStr	Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
title_full_unstemmed	Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
title_sort	dual rna-seq of orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/46adddfa7d4548f68077abbc70f1fb90
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Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen

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