Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity

Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and ly...

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Autores principales: Emilia Duarte-Williamson, Fiona Antony, Radu Rotarescu
Formato: article
Lenguaje:EN
Publicado: Mattioli1885 2012
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Acceso en línea:https://doaj.org/article/46c5bf0393584f15bacadbd1dbfbfb70
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spelling oai:doaj.org-article:46c5bf0393584f15bacadbd1dbfbfb702021-11-17T08:33:11ZSinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity2160-9381https://doaj.org/article/46c5bf0393584f15bacadbd1dbfbfb702012-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/991https://doaj.org/toc/2160-9381 Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and lymphocytes. Macrophages were aggregated in clusters resembling lymph node sinuses. Lymphophagocytosis or emperipolesis (the presence of an intact cell within the cytoplasm of another cell) was noted and the diagnosis of sinus histiocytosis established. Emilia Duarte-WilliamsonFiona AntonyRadu RotarescuMattioli1885articlehistiocytosissinus histiocytosisRosai-DorfmannoduleDermatologyRL1-803ENDermatology Practical & Conceptual (2012)
institution DOAJ
collection DOAJ
language EN
topic histiocytosis
sinus histiocytosis
Rosai-Dorfman
nodule
Dermatology
RL1-803
spellingShingle histiocytosis
sinus histiocytosis
Rosai-Dorfman
nodule
Dermatology
RL1-803
Emilia Duarte-Williamson
Fiona Antony
Radu Rotarescu
Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
description Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and lymphocytes. Macrophages were aggregated in clusters resembling lymph node sinuses. Lymphophagocytosis or emperipolesis (the presence of an intact cell within the cytoplasm of another cell) was noted and the diagnosis of sinus histiocytosis established.
format article
author Emilia Duarte-Williamson
Fiona Antony
Radu Rotarescu
author_facet Emilia Duarte-Williamson
Fiona Antony
Radu Rotarescu
author_sort Emilia Duarte-Williamson
title Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_short Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_full Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_fullStr Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_full_unstemmed Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_sort sinus histiocytosis (rosai- dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
publisher Mattioli1885
publishDate 2012
url https://doaj.org/article/46c5bf0393584f15bacadbd1dbfbfb70
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AT fionaantony sinushistiocytosisrosaidorfmandiseasepresentingwithsolitarycutaneousnoduleaveryrareclinicalentity
AT radurotarescu sinushistiocytosisrosaidorfmandiseasepresentingwithsolitarycutaneousnoduleaveryrareclinicalentity
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