Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and ly...
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Mattioli1885
2012
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oai:doaj.org-article:46c5bf0393584f15bacadbd1dbfbfb702021-11-17T08:33:11ZSinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity2160-9381https://doaj.org/article/46c5bf0393584f15bacadbd1dbfbfb702012-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/991https://doaj.org/toc/2160-9381 Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and lymphocytes. Macrophages were aggregated in clusters resembling lymph node sinuses. Lymphophagocytosis or emperipolesis (the presence of an intact cell within the cytoplasm of another cell) was noted and the diagnosis of sinus histiocytosis established. Emilia Duarte-WilliamsonFiona AntonyRadu RotarescuMattioli1885articlehistiocytosissinus histiocytosisRosai-DorfmannoduleDermatologyRL1-803ENDermatology Practical & Conceptual (2012) |
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histiocytosis sinus histiocytosis Rosai-Dorfman nodule Dermatology RL1-803 |
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histiocytosis sinus histiocytosis Rosai-Dorfman nodule Dermatology RL1-803 Emilia Duarte-Williamson Fiona Antony Radu Rotarescu Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity |
description |
Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and lymphocytes. Macrophages were aggregated in clusters resembling lymph node sinuses. Lymphophagocytosis or emperipolesis (the presence of an intact cell within the cytoplasm of another cell) was noted and the diagnosis of sinus histiocytosis established.
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format |
article |
author |
Emilia Duarte-Williamson Fiona Antony Radu Rotarescu |
author_facet |
Emilia Duarte-Williamson Fiona Antony Radu Rotarescu |
author_sort |
Emilia Duarte-Williamson |
title |
Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity |
title_short |
Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity |
title_full |
Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity |
title_fullStr |
Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity |
title_full_unstemmed |
Sinus histiocytosis (Rosai- Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity |
title_sort |
sinus histiocytosis (rosai- dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity |
publisher |
Mattioli1885 |
publishDate |
2012 |
url |
https://doaj.org/article/46c5bf0393584f15bacadbd1dbfbfb70 |
work_keys_str_mv |
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_version_ |
1718425668308434944 |