Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay.

Adiponectin, the adipose-derived hormone, plays an important role in the suppression of metabolic disorders that can result in type 2 diabetes, obesity, and atherosclerosis. It has been shown that up-regulation of adiponectin or adiponectin receptor has a number of therapeutic benefits. Given that i...

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Main Authors: Yiyi Sun, Zhihe Zang, Ling Zhong, Min Wu, Qing Su, Xiurong Gao, Wang Zan, Dong Lin, Yan Zhao, Zhonglin Zhang
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/46d1e5eb95024aab8493a46e430b0493
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