Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study
Background: This study aimed to quantify the proportion of participants with chronic kidney disease (CKD) and associated metabolic risk factors in a middle-aged and elderly population in Guishan District, Taoyuan City, Taiwan.Methods: This cross-sectional study enrolled residents aged 50–90 years li...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:46d6aafdaa62489182fe8304480919d02021-11-16T05:31:54ZMetabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study2296-858X10.3389/fmed.2021.748037https://doaj.org/article/46d6aafdaa62489182fe8304480919d02021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.748037/fullhttps://doaj.org/toc/2296-858XBackground: This study aimed to quantify the proportion of participants with chronic kidney disease (CKD) and associated metabolic risk factors in a middle-aged and elderly population in Guishan District, Taoyuan City, Taiwan.Methods: This cross-sectional study enrolled residents aged 50–90 years living in one community. All participants received a standardized personal interview, including a structured questionnaire, anthropometric measurements, and blood samples collected for laboratory testing. CKD was defined as the presence of kidney damage (urine albumin-creatinine ratio ≥30 mg/g) or estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2. Multiple logistic regression models were used to evaluate the risk factors associated with CKD.Results: A total of 400 participants were enrolled. The overall proportion of participants with CKD was 20.5% (95% confidence interval [CI]: 16.54–24.46%). The proportions of participants with CKD among those aged 50–64, 65–74, and 75 years and over were 17.7, 18.8, and 35.7%, respectively (p = 0.01). Multiple logistic regression model revealed that elevated blood pressure (odds ratio [OR] = 2.23, 95% CI: 1.16–4.30), hyperglycemia (OR = 2.87, 95% CI: 1.64–5.00), hyperuricemia (OR = 1.38, 95% CI: 1.14–1.69), and metabolic syndrome (OR = 2.30, 95% CI: 1.31–4.06) were significantly associated with CKD.Conclusions: The prevalence of CKD in the study population was high. Hypertension, hyperglycemia, hyperuricemia, and metabolic syndrome are significantly associated with CKD in a middle-aged and elderly population in Taiwan.Mei-Chun LuI-Ju ChenLe-Tien HsuYing-Jen ChenMeng-Ting TsouMeng-Ting TsouTao-Hsin TungJau-Yuan ChenJau-Yuan ChenFrontiers Media S.A.articlechronic kidney diseaseprevalencemiddle-aged and elderlymetabolic risk factorsmetabolic syndromeMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021) |
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DOAJ |
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EN |
| topic |
chronic kidney disease prevalence middle-aged and elderly metabolic risk factors metabolic syndrome Medicine (General) R5-920 |
| spellingShingle |
chronic kidney disease prevalence middle-aged and elderly metabolic risk factors metabolic syndrome Medicine (General) R5-920 Mei-Chun Lu I-Ju Chen Le-Tien Hsu Ying-Jen Chen Meng-Ting Tsou Meng-Ting Tsou Tao-Hsin Tung Jau-Yuan Chen Jau-Yuan Chen Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study |
| description |
Background: This study aimed to quantify the proportion of participants with chronic kidney disease (CKD) and associated metabolic risk factors in a middle-aged and elderly population in Guishan District, Taoyuan City, Taiwan.Methods: This cross-sectional study enrolled residents aged 50–90 years living in one community. All participants received a standardized personal interview, including a structured questionnaire, anthropometric measurements, and blood samples collected for laboratory testing. CKD was defined as the presence of kidney damage (urine albumin-creatinine ratio ≥30 mg/g) or estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2. Multiple logistic regression models were used to evaluate the risk factors associated with CKD.Results: A total of 400 participants were enrolled. The overall proportion of participants with CKD was 20.5% (95% confidence interval [CI]: 16.54–24.46%). The proportions of participants with CKD among those aged 50–64, 65–74, and 75 years and over were 17.7, 18.8, and 35.7%, respectively (p = 0.01). Multiple logistic regression model revealed that elevated blood pressure (odds ratio [OR] = 2.23, 95% CI: 1.16–4.30), hyperglycemia (OR = 2.87, 95% CI: 1.64–5.00), hyperuricemia (OR = 1.38, 95% CI: 1.14–1.69), and metabolic syndrome (OR = 2.30, 95% CI: 1.31–4.06) were significantly associated with CKD.Conclusions: The prevalence of CKD in the study population was high. Hypertension, hyperglycemia, hyperuricemia, and metabolic syndrome are significantly associated with CKD in a middle-aged and elderly population in Taiwan. |
| format |
article |
| author |
Mei-Chun Lu I-Ju Chen Le-Tien Hsu Ying-Jen Chen Meng-Ting Tsou Meng-Ting Tsou Tao-Hsin Tung Jau-Yuan Chen Jau-Yuan Chen |
| author_facet |
Mei-Chun Lu I-Ju Chen Le-Tien Hsu Ying-Jen Chen Meng-Ting Tsou Meng-Ting Tsou Tao-Hsin Tung Jau-Yuan Chen Jau-Yuan Chen |
| author_sort |
Mei-Chun Lu |
| title |
Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study |
| title_short |
Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study |
| title_full |
Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study |
| title_fullStr |
Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study |
| title_full_unstemmed |
Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study |
| title_sort |
metabolic risk factors associated with chronic kidney disease in a middle-aged and elderly taiwanese population: a cross-sectional study |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/46d6aafdaa62489182fe8304480919d0 |
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