CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study

Fernanda Cabral Soares,1 Thaís Cristina Galdino de Oliveira,1 Liliane Dias e Dias de Macedo,1 Alessandra Mendonça Tomás,1 Domingos Luiz Wanderley Picanço-Diniz,2 João Bento-Torres,1,3 Natáli Valim Oliver Bento-Torres,1,3 Cristovam Wan...

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Autores principales:	Cabral Soares F, Oliveira TCG, Macedo LDD, Tomás AM, Picanço-Diniz DLW, Bento-Torres J, Bento-Torres NVO, Picanço-Diniz CW
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	aging neuropsychological tests cluster analysis discriminant analysis ROC analysis Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/46e4a759bb5e467481a49dc8365c2883
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spelling	oai:doaj.org-article:46e4a759bb5e467481a49dc8365c28832021-12-02T03:20:50ZCANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study1178-1998https://doaj.org/article/46e4a759bb5e467481a49dc8365c28832014-12-01T00:00:00Zhttps://www.dovepress.com/cantab-object-recognition-and-language-tests-to-detect-aging-cognitive-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Fernanda Cabral Soares,1 Thaís Cristina Galdino de Oliveira,1 Liliane Dias e Dias de Macedo,1 Alessandra Mendonça Tomás,1 Domingos Luiz Wanderley Picanço-Diniz,2 João Bento-Torres,1,3 Natáli Valim Oliver Bento-Torres,1,3 Cristovam Wanderley Picanço-Diniz1 1Universidade Federal do Pará, Instituto de Ciências Biológicas, Hospital Universitário João de Barros Barreto, Laboratório de Investigações em Neurodegeneração e Infecção Belém, Pará, Brazil; 2Universidade Federal do Oeste do Pará, Núcleo Universitário de Oriximiná, Oriximiná, Pará, Brazil; 3Faculdade de Fisioterapia e Terapia Ocupacional, Universidade Federal do Pará, Belém, Pará, BrazilObjective: The recognition of the limits between normal and pathological aging is essential to start preventive actions. The aim of this paper is to compare the Cambridge Neuropsychological Test Automated Battery (CANTAB) and language tests to distinguish subtle differences in cognitive performances in two different age groups, namely young adults and elderly cognitively normal subjects.Method: We selected 29 young adults (29.9±1.06 years) and 31 older adults (74.1±1.15 years) matched by educational level (years of schooling). All subjects underwent a general assessment and a battery of neuropsychological tests, including the Mini Mental State Examination, visuospatial learning, and memory tasks from CANTAB and language tests. Cluster and discriminant analysis were applied to all neuropsychological test results to distinguish possible subgroups inside each age group.Results: Significant differences in the performance of aged and young adults were detected in both language and visuospatial memory tests. Intragroup cluster and discriminant analysis revealed that CANTAB, as compared to language tests, was able to detect subtle but significant differences between the subjects.Conclusion: Based on these findings, we concluded that, as compared to language tests, large-scale application of automated visuospatial tests to assess learning and memory might increase our ability to discern the limits between normal and pathological aging. Keywords: aging, neuropsychological tests, cluster analysis, discriminant analysisCabral Soares FOliveira TCGMacedo LDDTomás AMPicanço-Diniz DLWBento-Torres JBento-Torres NVOPicanço-Diniz CWDove Medical Pressarticleagingneuropsychological testscluster analysisdiscriminant analysisROC analysisGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 10, Pp 37-48 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	aging neuropsychological tests cluster analysis discriminant analysis ROC analysis Geriatrics RC952-954.6
spellingShingle	aging neuropsychological tests cluster analysis discriminant analysis ROC analysis Geriatrics RC952-954.6 Cabral Soares F Oliveira TCG Macedo LDD Tomás AM Picanço-Diniz DLW Bento-Torres J Bento-Torres NVO Picanço-Diniz CW CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study
description	Fernanda Cabral Soares,1 Thaís Cristina Galdino de Oliveira,1 Liliane Dias e Dias de Macedo,1 Alessandra Mendonça Tomás,1 Domingos Luiz Wanderley Picanço-Diniz,2 João Bento-Torres,1,3 Natáli Valim Oliver Bento-Torres,1,3 Cristovam Wanderley Picanço-Diniz1 1Universidade Federal do Pará, Instituto de Ciências Biológicas, Hospital Universitário João de Barros Barreto, Laboratório de Investigações em Neurodegeneração e Infecção Belém, Pará, Brazil; 2Universidade Federal do Oeste do Pará, Núcleo Universitário de Oriximiná, Oriximiná, Pará, Brazil; 3Faculdade de Fisioterapia e Terapia Ocupacional, Universidade Federal do Pará, Belém, Pará, BrazilObjective: The recognition of the limits between normal and pathological aging is essential to start preventive actions. The aim of this paper is to compare the Cambridge Neuropsychological Test Automated Battery (CANTAB) and language tests to distinguish subtle differences in cognitive performances in two different age groups, namely young adults and elderly cognitively normal subjects.Method: We selected 29 young adults (29.9±1.06 years) and 31 older adults (74.1±1.15 years) matched by educational level (years of schooling). All subjects underwent a general assessment and a battery of neuropsychological tests, including the Mini Mental State Examination, visuospatial learning, and memory tasks from CANTAB and language tests. Cluster and discriminant analysis were applied to all neuropsychological test results to distinguish possible subgroups inside each age group.Results: Significant differences in the performance of aged and young adults were detected in both language and visuospatial memory tests. Intragroup cluster and discriminant analysis revealed that CANTAB, as compared to language tests, was able to detect subtle but significant differences between the subjects.Conclusion: Based on these findings, we concluded that, as compared to language tests, large-scale application of automated visuospatial tests to assess learning and memory might increase our ability to discern the limits between normal and pathological aging. Keywords: aging, neuropsychological tests, cluster analysis, discriminant analysis
format	article
author	Cabral Soares F Oliveira TCG Macedo LDD Tomás AM Picanço-Diniz DLW Bento-Torres J Bento-Torres NVO Picanço-Diniz CW
author_facet	Cabral Soares F Oliveira TCG Macedo LDD Tomás AM Picanço-Diniz DLW Bento-Torres J Bento-Torres NVO Picanço-Diniz CW
author_sort	Cabral Soares F
title	CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study
title_short	CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study
title_full	CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study
title_fullStr	CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study
title_full_unstemmed	CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study
title_sort	cantab object recognition and language tests to detect aging cognitive decline: an exploratory comparative study
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/46e4a759bb5e467481a49dc8365c2883
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CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study

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