High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks

Cellular delivery of proteins is currently limited by inefficient release from their carrier or by altering the protein structure after chemical modification. Here the authors use metal-organic frameworks which act as nanofactories and show a supported enzymatic activity for an extended period of ti...

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Autores principales:	Xizhen Lian, Alfredo Erazo-Oliveras, Jean-Philippe Pellois, Hong-Cai Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/46e75d82863347758ffeb9de3527941e
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spelling	oai:doaj.org-article:46e75d82863347758ffeb9de3527941e2021-12-02T14:41:20ZHigh efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks10.1038/s41467-017-02103-02041-1723https://doaj.org/article/46e75d82863347758ffeb9de3527941e2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02103-0https://doaj.org/toc/2041-1723Cellular delivery of proteins is currently limited by inefficient release from their carrier or by altering the protein structure after chemical modification. Here the authors use metal-organic frameworks which act as nanofactories and show a supported enzymatic activity for an extended period of time.Xizhen LianAlfredo Erazo-OliverasJean-Philippe PelloisHong-Cai ZhouNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xizhen Lian Alfredo Erazo-Oliveras Jean-Philippe Pellois Hong-Cai Zhou High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks
description	Cellular delivery of proteins is currently limited by inefficient release from their carrier or by altering the protein structure after chemical modification. Here the authors use metal-organic frameworks which act as nanofactories and show a supported enzymatic activity for an extended period of time.
format	article
author	Xizhen Lian Alfredo Erazo-Oliveras Jean-Philippe Pellois Hong-Cai Zhou
author_facet	Xizhen Lian Alfredo Erazo-Oliveras Jean-Philippe Pellois Hong-Cai Zhou
author_sort	Xizhen Lian
title	High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks
title_short	High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks
title_full	High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks
title_fullStr	High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks
title_full_unstemmed	High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks
title_sort	high efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/46e75d82863347758ffeb9de3527941e
work_keys_str_mv	AT xizhenlian highefficiencyandlongtermintracellularactivityofanenzymaticnanofactorybasedonmetalorganicframeworks AT alfredoerazooliveras highefficiencyandlongtermintracellularactivityofanenzymaticnanofactorybasedonmetalorganicframeworks AT jeanphilippepellois highefficiencyandlongtermintracellularactivityofanenzymaticnanofactorybasedonmetalorganicframeworks AT hongcaizhou highefficiencyandlongtermintracellularactivityofanenzymaticnanofactorybasedonmetalorganicframeworks
_version_	1718389927246299136

High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks

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