Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4

Armadillo (ARM) family proteins can act as oncogenes or tumor suppressors. Here, the authors show that a new ARM protein (ARMC12) is upregulated in neuroblastoma, binds the PRC2 component RBBP4, and inhibits transcription of tumor suppressive genes.

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Autores principales: Dan Li, Huajie Song, Hong Mei, Erhu Fang, Xiaojing Wang, Feng Yang, Huanhuan Li, Yajun Chen, Kai Huang, Liduan Zheng, Qiangsong Tong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/46fa6a22480b40dc9cccd28b7a9bc751
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