Genetic variation in the TNF gene is associated with susceptibility to severe sepsis, but not with mortality.

Genetic variation in the TNF gene is associated with susceptibility to severe sepsis, but not with mortality.

<h4>Background</h4>Tumor necrosis factor (TNF) and TNF receptor superfamily (TNFR)-mediated immune response play an essential role in the pathogenesis of severe sepsis. Studies examining associations of TNF and lymphotoxin-α (LTA) single nucleotide polymorphisms (SNPs) with severe sepsis...

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Autores principales: Zhenju Song, Yuanlin Song, Jun Yin, Yao Shen, Chenling Yao, Zhan Sun, Jinjun Jiang, Duming Zhu, Yong Zhang, Qinjun Shen, Lei Gao, Chaoyang Tong, Chunxue Bai
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4702737213a34009bf13bdbf3db16f2a
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