Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney.

Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney.

The NaCl cotransporter (NCC) is essential for sodium reabsorption at the distal convoluted tubules (DCT), and its phosphorylation increases its transport activity and apical membrane localization. Although insulin has been reported to increase sodium reabsorption in the kidney, the linkage between i...

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Autores principales: Eisei Sohara, Tatemitsu Rai, Sung-Sen Yang, Akihito Ohta, Shotaro Naito, Motoko Chiga, Naohiro Nomura, Shih-Hua Lin, Alain Vandewalle, Eriko Ohta, Sei Sasaki, Shinichi Uchida
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4709656b57e24eb48f568365ced81cab
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