Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape
Mitosis poses a challenge for transcriptional programs, as it is thought that several proteins lose binding on condensed chromosomes. Here, the authors analyze the chromatin-bound proteome through the cell cycle, revealing retention of most transcription factors and preservation of the regulatory la...
Saved in:
Main Authors: | Paul Adrian Ginno, Lukas Burger, Jan Seebacher, Vytautas Iesmantavicius, Dirk Schübeler |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/471b40b50d8c49149705427b2d4eb93f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Chromatin modifier MTA1 regulates mitotic transition and tumorigenesis by orchestrating mitotic mRNA processing
by: Jian Liu, et al.
Published: (2020) -
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation
by: Jingxue Xin, et al.
Published: (2020) -
The RAD51 recombinase protects mitotic chromatin in human cells
by: Isabel E. Wassing, et al.
Published: (2021) -
A possible role of Drosophila CTCF in mitotic bookmarking and maintaining chromatin domains during the cell cycle
by: Shen,Wenlong, et al.
Published: (2015) -
Premitotic assembly of human CENPs -T and -W switches centromeric chromatin to a mitotic state.
by: Lisa Prendergast, et al.
Published: (2011)