Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape
Mitosis poses a challenge for transcriptional programs, as it is thought that several proteins lose binding on condensed chromosomes. Here, the authors analyze the chromatin-bound proteome through the cell cycle, revealing retention of most transcription factors and preservation of the regulatory la...
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Auteurs principaux: | Paul Adrian Ginno, Lukas Burger, Jan Seebacher, Vytautas Iesmantavicius, Dirk Schübeler |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/471b40b50d8c49149705427b2d4eb93f |
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