Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

Mitosis poses a challenge for transcriptional programs, as it is thought that several proteins lose binding on condensed chromosomes. Here, the authors analyze the chromatin-bound proteome through the cell cycle, revealing retention of most transcription factors and preservation of the regulatory la...

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Bibliographic Details
Main Authors: Paul Adrian Ginno, Lukas Burger, Jan Seebacher, Vytautas Iesmantavicius, Dirk Schübeler
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/471b40b50d8c49149705427b2d4eb93f
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