Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4

A G1 cell cycle regulatory kinase Cip1 has been identified in budding yeast but how this is regulated is unclear. Here the authors identify cell cycle (Mcm1) and stress-mediated (Msn 2/4) transcription factors as regulating Cip1, causing stress induced CDK inhibition and delay in cell cycle progress...

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Autores principales:	Ya-Lan Chang, Shun-Fu Tseng, Yu-Ching Huang, Zih-Jie Shen, Pang-Hung Hsu, Meng-Hsun Hsieh, Chia-Wei Yang, Silvia Tognetti, Berta Canal, Laia Subirana, Chien-Wei Wang, Hsiao-Tan Chen, Chi-Ying Lin, Francesc Posas, Shu-Chun Teng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/471f7f9a1954498791ddcc5b39f8dc56
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spelling	oai:doaj.org-article:471f7f9a1954498791ddcc5b39f8dc562021-12-02T14:16:04ZYeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/410.1038/s41467-017-00080-y2041-1723https://doaj.org/article/471f7f9a1954498791ddcc5b39f8dc562017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00080-yhttps://doaj.org/toc/2041-1723A G1 cell cycle regulatory kinase Cip1 has been identified in budding yeast but how this is regulated is unclear. Here the authors identify cell cycle (Mcm1) and stress-mediated (Msn 2/4) transcription factors as regulating Cip1, causing stress induced CDK inhibition and delay in cell cycle progression.Ya-Lan ChangShun-Fu TsengYu-Ching HuangZih-Jie ShenPang-Hung HsuMeng-Hsun HsiehChia-Wei YangSilvia TognettiBerta CanalLaia SubiranaChien-Wei WangHsiao-Tan ChenChi-Ying LinFrancesc PosasShu-Chun TengNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ya-Lan Chang Shun-Fu Tseng Yu-Ching Huang Zih-Jie Shen Pang-Hung Hsu Meng-Hsun Hsieh Chia-Wei Yang Silvia Tognetti Berta Canal Laia Subirana Chien-Wei Wang Hsiao-Tan Chen Chi-Ying Lin Francesc Posas Shu-Chun Teng Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4
description	A G1 cell cycle regulatory kinase Cip1 has been identified in budding yeast but how this is regulated is unclear. Here the authors identify cell cycle (Mcm1) and stress-mediated (Msn 2/4) transcription factors as regulating Cip1, causing stress induced CDK inhibition and delay in cell cycle progression.
format	article
author	Ya-Lan Chang Shun-Fu Tseng Yu-Ching Huang Zih-Jie Shen Pang-Hung Hsu Meng-Hsun Hsieh Chia-Wei Yang Silvia Tognetti Berta Canal Laia Subirana Chien-Wei Wang Hsiao-Tan Chen Chi-Ying Lin Francesc Posas Shu-Chun Teng
author_facet	Ya-Lan Chang Shun-Fu Tseng Yu-Ching Huang Zih-Jie Shen Pang-Hung Hsu Meng-Hsun Hsieh Chia-Wei Yang Silvia Tognetti Berta Canal Laia Subirana Chien-Wei Wang Hsiao-Tan Chen Chi-Ying Lin Francesc Posas Shu-Chun Teng
author_sort	Ya-Lan Chang
title	Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4
title_short	Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4
title_full	Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4
title_fullStr	Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4
title_full_unstemmed	Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4
title_sort	yeast cip1 is activated by environmental stress to inhibit cdk1–g1 cyclins via mcm1 and msn2/4
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/471f7f9a1954498791ddcc5b39f8dc56
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Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4

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