Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface

Aizhu Tao,1,3 Kristen A Peterson,2 Hong Jiang,1 Yilei Shao,1,3 Jianguang Zhong,1,4 Frank C Carey,2 Elias P Rosen,2 Jianhua Wang11Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA; 2Southwest Sciences, Inc, Santa Fe, NM, USA; 3School of Ophthalmology and Optometry, Wenzhou Medical Coll...

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Autores principales:	Tao A, Peterson KA, Jiang H, Shao Y, Zhong J, Carey FC, Rosen EP, Wang J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/472c9cc0cbfe484585f0cfa6da62e46e
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spelling	oai:doaj.org-article:472c9cc0cbfe484585f0cfa6da62e46e2021-12-02T02:07:30ZUltra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface1177-54671177-5483https://doaj.org/article/472c9cc0cbfe484585f0cfa6da62e46e2013-08-01T00:00:00Zhttp://www.dovepress.com/ultra-high-resolution-and-long-scan-depth-optical-coherence-tomography-a13995https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Aizhu Tao,1,3 Kristen A Peterson,2 Hong Jiang,1 Yilei Shao,1,3 Jianguang Zhong,1,4 Frank C Carey,2 Elias P Rosen,2 Jianhua Wang11Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA; 2Southwest Sciences, Inc, Santa Fe, NM, USA; 3School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, People's Republic of China; 4Department of Ophthalmology, Hangzhou First People's Hospital, Hangzhou, People's Republic of ChinaAbstract: We used a unique combination of four state-of-the-art technologies to achieve a high performance spectral domain optical coherence tomography system suitable for imaging the entire ocular surface. An ultra-high resolution, extended depth range, full-phase interferometry, and high-speed complementary metal-oxide semiconductor transistor camera detection provided unprecedented performance for the precise quantification of a wide range of the ocular surface. We demonstrated the feasibility of this approach by obtaining high-speed and high-resolution images of a model eye beyond the corneal–scleral junction. Surfaces determined from the images with a segmentation algorithm demonstrated excellent accuracy and precision.Keywords: ocular surface, complex, full range, optical coherence tomographyTao APeterson KAJiang HShao YZhong JCarey FCRosen EPWang JDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1623-1633 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Tao A Peterson KA Jiang H Shao Y Zhong J Carey FC Rosen EP Wang J Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface
description	Aizhu Tao,1,3 Kristen A Peterson,2 Hong Jiang,1 Yilei Shao,1,3 Jianguang Zhong,1,4 Frank C Carey,2 Elias P Rosen,2 Jianhua Wang11Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA; 2Southwest Sciences, Inc, Santa Fe, NM, USA; 3School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, People's Republic of China; 4Department of Ophthalmology, Hangzhou First People's Hospital, Hangzhou, People's Republic of ChinaAbstract: We used a unique combination of four state-of-the-art technologies to achieve a high performance spectral domain optical coherence tomography system suitable for imaging the entire ocular surface. An ultra-high resolution, extended depth range, full-phase interferometry, and high-speed complementary metal-oxide semiconductor transistor camera detection provided unprecedented performance for the precise quantification of a wide range of the ocular surface. We demonstrated the feasibility of this approach by obtaining high-speed and high-resolution images of a model eye beyond the corneal–scleral junction. Surfaces determined from the images with a segmentation algorithm demonstrated excellent accuracy and precision.Keywords: ocular surface, complex, full range, optical coherence tomography
format	article
author	Tao A Peterson KA Jiang H Shao Y Zhong J Carey FC Rosen EP Wang J
author_facet	Tao A Peterson KA Jiang H Shao Y Zhong J Carey FC Rosen EP Wang J
author_sort	Tao A
title	Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface
title_short	Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface
title_full	Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface
title_fullStr	Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface
title_full_unstemmed	Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface
title_sort	ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/472c9cc0cbfe484585f0cfa6da62e46e
work_keys_str_mv	AT taoa ultrahighresolutionandlongscandepthopticalcoherencetomographywithfullphasedetectionforimagingtheocularsurface AT petersonka ultrahighresolutionandlongscandepthopticalcoherencetomographywithfullphasedetectionforimagingtheocularsurface AT jiangh ultrahighresolutionandlongscandepthopticalcoherencetomographywithfullphasedetectionforimagingtheocularsurface AT shaoy ultrahighresolutionandlongscandepthopticalcoherencetomographywithfullphasedetectionforimagingtheocularsurface AT zhongj ultrahighresolutionandlongscandepthopticalcoherencetomographywithfullphasedetectionforimagingtheocularsurface AT careyfc ultrahighresolutionandlongscandepthopticalcoherencetomographywithfullphasedetectionforimagingtheocularsurface AT rosenep ultrahighresolutionandlongscandepthopticalcoherencetomographywithfullphasedetectionforimagingtheocularsurface AT wangj ultrahighresolutionandlongscandepthopticalcoherencetomographywithfullphasedetectionforimagingtheocularsurface
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Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface

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