Direct induction of chondrogenic cells from human dermal fibroblast culture by defined factors.
The repair of large cartilage defects with hyaline cartilage continues to be a challenging clinical issue. We recently reported that the forced expression of two reprogramming factors (c-Myc and Klf4) and one chondrogenic factor (SOX9) can induce chondrogenic cells from mouse dermal fibroblast cultu...
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Autores principales: | Hidetatsu Outani, Minoru Okada, Akihiro Yamashita, Kanako Nakagawa, Hideki Yoshikawa, Noriyuki Tsumaki |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/47374c2ce230426a9ab4d2f778013157 |
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