Direct induction of chondrogenic cells from human dermal fibroblast culture by defined factors.

The repair of large cartilage defects with hyaline cartilage continues to be a challenging clinical issue. We recently reported that the forced expression of two reprogramming factors (c-Myc and Klf4) and one chondrogenic factor (SOX9) can induce chondrogenic cells from mouse dermal fibroblast cultu...

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Autores principales: Hidetatsu Outani, Minoru Okada, Akihiro Yamashita, Kanako Nakagawa, Hideki Yoshikawa, Noriyuki Tsumaki
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/47374c2ce230426a9ab4d2f778013157
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