Cholesterol modified DP7 and pantothenic acid induce dendritic cell homing to enhance the efficacy of dendritic cell vaccines

Abstract Dendritic cell (DC)-based cancer vaccines have so far achieved good therapeutic effects in animal experiments and early clinical trials for certain malignant tumors. However, the overall objective response rate in clinical trials rarely exceeds 15%. The poor efficiency of DC migration to ly...

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Autores principales: Rui Zhang, Lin Tang, Qing Li, Yaomei Tian, Binyan Zhao, Bailing Zhou, Li Yang
Formato: article
Lenguaje:EN
Publicado: Springer 2021
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Acceso en línea:https://doaj.org/article/473fc7fe717c4bc6b718b431e9beb70b
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