Virus lasers for biological detection

Many ligand-binding assays still rely on signals that scale linearly with probe concentration. The authors present lasing detection probes with a dye-labelled virus as the gain medium to optically amplify the signal, which could enable much higher signals than for fluorescent quantification.

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Detalles Bibliográficos
Autores principales: John E. Hales, Guy Matmon, Paul A. Dalby, John M. Ward, Gabriel Aeppli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/4746f5b48ed545339ebf1a0fdd9a36c1
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Descripción
Sumario:Many ligand-binding assays still rely on signals that scale linearly with probe concentration. The authors present lasing detection probes with a dye-labelled virus as the gain medium to optically amplify the signal, which could enable much higher signals than for fluorescent quantification.