Virus lasers for biological detection

Many ligand-binding assays still rely on signals that scale linearly with probe concentration. The authors present lasing detection probes with a dye-labelled virus as the gain medium to optically amplify the signal, which could enable much higher signals than for fluorescent quantification.

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Detalles Bibliográficos
Autores principales:	John E. Hales, Guy Matmon, Paul A. Dalby, John M. Ward, Gabriel Aeppli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4746f5b48ed545339ebf1a0fdd9a36c1
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id	oai:doaj.org-article:4746f5b48ed545339ebf1a0fdd9a36c1
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spelling	oai:doaj.org-article:4746f5b48ed545339ebf1a0fdd9a36c12021-12-02T17:32:56ZVirus lasers for biological detection10.1038/s41467-019-11604-z2041-1723https://doaj.org/article/4746f5b48ed545339ebf1a0fdd9a36c12019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11604-zhttps://doaj.org/toc/2041-1723Many ligand-binding assays still rely on signals that scale linearly with probe concentration. The authors present lasing detection probes with a dye-labelled virus as the gain medium to optically amplify the signal, which could enable much higher signals than for fluorescent quantification.John E. HalesGuy MatmonPaul A. DalbyJohn M. WardGabriel AeppliNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q John E. Hales Guy Matmon Paul A. Dalby John M. Ward Gabriel Aeppli Virus lasers for biological detection
description	Many ligand-binding assays still rely on signals that scale linearly with probe concentration. The authors present lasing detection probes with a dye-labelled virus as the gain medium to optically amplify the signal, which could enable much higher signals than for fluorescent quantification.
format	article
author	John E. Hales Guy Matmon Paul A. Dalby John M. Ward Gabriel Aeppli
author_facet	John E. Hales Guy Matmon Paul A. Dalby John M. Ward Gabriel Aeppli
author_sort	John E. Hales
title	Virus lasers for biological detection
title_short	Virus lasers for biological detection
title_full	Virus lasers for biological detection
title_fullStr	Virus lasers for biological detection
title_full_unstemmed	Virus lasers for biological detection
title_sort	virus lasers for biological detection
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/4746f5b48ed545339ebf1a0fdd9a36c1
work_keys_str_mv	AT johnehales viruslasersforbiologicaldetection AT guymatmon viruslasersforbiologicaldetection AT pauladalby viruslasersforbiologicaldetection AT johnmward viruslasersforbiologicaldetection AT gabrielaeppli viruslasersforbiologicaldetection
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Virus lasers for biological detection

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