Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound

Vassilis Papayiannis,1 Konstantinos T Tsaousis,2,3 Constantinos A Kouskouras,4 Afroditi Haritanti,4 Vasilios F Diakonis,5 Ioannis T Tsinopoulos2 1Department of Radiology, Papageorgiou General Hospital, 2Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece; 3John A...

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Autores principales:	Papayiannis V, Tsaousis KT, Kouskouras CA, Haritanti A, Diakonis VF, Tsinopoulos IT
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	choroidal melanoma Ultrasound scan MRI imaging characteristics retinal detachment Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/474a63f769bb4c91a89ce52641e5f675
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spelling	oai:doaj.org-article:474a63f769bb4c91a89ce52641e5f6752021-12-02T03:49:06ZInvestigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound1177-5483https://doaj.org/article/474a63f769bb4c91a89ce52641e5f6752017-08-01T00:00:00Zhttps://www.dovepress.com/investigation-into-the-quantitative-and-qualitative-characteristics-of-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Vassilis Papayiannis,1 Konstantinos T Tsaousis,2,3 Constantinos A Kouskouras,4 Afroditi Haritanti,4 Vasilios F Diakonis,5 Ioannis T Tsinopoulos2 1Department of Radiology, Papageorgiou General Hospital, 2Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece; 3John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA; 4Department of Radiology, AHEPA Aristotle University Hospital of Thessaloniki, Thessaloniki, Greece; 5Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, USA Objective: To investigate the homogeneity and vascularity of choroidal melanoma through magnetic resonance imaging (MRI) and brightness modulation (B-mode) ultrasound scan and their correlation with dimensions of tumor, as well as to measure the sensitivity of both modalities in retinal detachment (RD) detection.Materials and methods: This retrospective chart review included patients diagnosed with choroidal melanoma. All these patients underwent MRI scans using T2-weighted (T2-WI) and T1-weighted (T1-WI) sequences, before and after an intravenous injection of paramagnetic contrast material. The patients were also examined using a B-mode ultrasound scan, and the results from both modalities were compared (tumor homogeneity, tumor height, tumor base diameter, and tumor vascularity).Results: Forty-two patients (mean age =65.33±12.51 years) with choroidal melanoma were included in the study. Homogeneity was confirmed in 16 patients through ultrasound scan, in 19 patients through T1-WI sequence, in 21 patients through T2-WI sequence, and in 25 patients through T1-WI sequence + contrast (gadolinium). Patients with homogenous tumors presented with lower (P=0.0045) mean height than that of those with nonhomogenous tumors, whereas no statistically significant difference was found for base diameter measurements (P=0.056). Patients with tumors of high vascularity presented with greater mean height (P=0.000638) and greater mean base diameter compared with those with tumors of low vascularity (P=0.019543). RD was detected in 26 patients through T1-WI sequence, in 13 patients through T2-WI sequence, in 26 patients through T1-WI sequence + contrast, and in 32 patients through ultrasound scan, which proved to be the most sensitive modality.Conclusion: The height of choroidal melanoma was positively correlated with tumor’s homogeneity. Melanomas of greater height were found to be less homogenous, due to increased degeneration and higher occurrence of intratumoral hemorrhage. In addition, choroidal melanoma’s height was also positively correlated with the level of its vascularity. Finally, ultrasound scan was found to be more sensitive than MRI in the detection of RD. Keywords: homogeneity, vascularity, ultrasound scan, MRI, imaging characteristics, retinal detachmentPapayiannis VTsaousis KTKouskouras CAHaritanti ADiakonis VFTsinopoulos ITDove Medical Pressarticlechoroidal melanomaUltrasound scanMRIimaging characteristicsretinal detachmentOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 1557-1564 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	choroidal melanoma Ultrasound scan MRI imaging characteristics retinal detachment Ophthalmology RE1-994
spellingShingle	choroidal melanoma Ultrasound scan MRI imaging characteristics retinal detachment Ophthalmology RE1-994 Papayiannis V Tsaousis KT Kouskouras CA Haritanti A Diakonis VF Tsinopoulos IT Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound
description	Vassilis Papayiannis,1 Konstantinos T Tsaousis,2,3 Constantinos A Kouskouras,4 Afroditi Haritanti,4 Vasilios F Diakonis,5 Ioannis T Tsinopoulos2 1Department of Radiology, Papageorgiou General Hospital, 2Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece; 3John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA; 4Department of Radiology, AHEPA Aristotle University Hospital of Thessaloniki, Thessaloniki, Greece; 5Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, USA Objective: To investigate the homogeneity and vascularity of choroidal melanoma through magnetic resonance imaging (MRI) and brightness modulation (B-mode) ultrasound scan and their correlation with dimensions of tumor, as well as to measure the sensitivity of both modalities in retinal detachment (RD) detection.Materials and methods: This retrospective chart review included patients diagnosed with choroidal melanoma. All these patients underwent MRI scans using T2-weighted (T2-WI) and T1-weighted (T1-WI) sequences, before and after an intravenous injection of paramagnetic contrast material. The patients were also examined using a B-mode ultrasound scan, and the results from both modalities were compared (tumor homogeneity, tumor height, tumor base diameter, and tumor vascularity).Results: Forty-two patients (mean age =65.33±12.51 years) with choroidal melanoma were included in the study. Homogeneity was confirmed in 16 patients through ultrasound scan, in 19 patients through T1-WI sequence, in 21 patients through T2-WI sequence, and in 25 patients through T1-WI sequence + contrast (gadolinium). Patients with homogenous tumors presented with lower (P=0.0045) mean height than that of those with nonhomogenous tumors, whereas no statistically significant difference was found for base diameter measurements (P=0.056). Patients with tumors of high vascularity presented with greater mean height (P=0.000638) and greater mean base diameter compared with those with tumors of low vascularity (P=0.019543). RD was detected in 26 patients through T1-WI sequence, in 13 patients through T2-WI sequence, in 26 patients through T1-WI sequence + contrast, and in 32 patients through ultrasound scan, which proved to be the most sensitive modality.Conclusion: The height of choroidal melanoma was positively correlated with tumor’s homogeneity. Melanomas of greater height were found to be less homogenous, due to increased degeneration and higher occurrence of intratumoral hemorrhage. In addition, choroidal melanoma’s height was also positively correlated with the level of its vascularity. Finally, ultrasound scan was found to be more sensitive than MRI in the detection of RD. Keywords: homogeneity, vascularity, ultrasound scan, MRI, imaging characteristics, retinal detachment
format	article
author	Papayiannis V Tsaousis KT Kouskouras CA Haritanti A Diakonis VF Tsinopoulos IT
author_facet	Papayiannis V Tsaousis KT Kouskouras CA Haritanti A Diakonis VF Tsinopoulos IT
author_sort	Papayiannis V
title	Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound
title_short	Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound
title_full	Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound
title_fullStr	Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound
title_full_unstemmed	Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound
title_sort	investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and b-scan ultrasound
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/474a63f769bb4c91a89ce52641e5f675
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Investigation into the quantitative and qualitative characteristics of choroidal melanoma through magnetic resonance imaging and B-scan ultrasound

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