Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy

Objective: For the treatment of obstructive sleep apnea in adults, mandibular advancement devices (MADs) are often used. Since adults with a prognathic mandibular phenotype are at risk of developing an unfavorable facial profile, midfacial development using biomimetic oral appliance therapy might pr...

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Autores principales:	G. Dave Singh, Hee Nam Kim
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2021
Materias:	Pneumatization Maxillary air sinus Biomimetic Oral appliance therapy Palatal expansion Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/474c2e2558f14f2987d9a6f913d7dd5e
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spelling	oai:doaj.org-article:474c2e2558f14f2987d9a6f913d7dd5e2021-12-02T16:44:57ZChanges in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy2095-881110.1016/j.wjorl.2020.07.007https://doaj.org/article/474c2e2558f14f2987d9a6f913d7dd5e2021-04-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881120301360https://doaj.org/toc/2095-8811Objective: For the treatment of obstructive sleep apnea in adults, mandibular advancement devices (MADs) are often used. Since adults with a prognathic mandibular phenotype are at risk of developing an unfavorable facial profile, midfacial development using biomimetic oral appliance therapy might provide a suitable alternative. However, the effect of this procedure on the maxillary air sinuses is unknown; therefore, changes in sinus pneumatization were investigated in this study. Methods: After obtaining informed consent, 16 consecutive Korean adults with midfacial hypoplasia had 3D cone-beam (CB) CT scans taken, and biomimetic upper appliances (DNA appliance®, Vivos Therapeutics, Inc., USA) were constructed.All subjects were instructed to wear the device 12–16 h/day. Each month, examination for the progress of midfacial development was recorded. Post-treatment, a follow-up 3D CBCT scan was undertaken with no device in the patient's mouth. Pre- and post-treatment linear and volumetric measurements were obtained using appropriate software, and compared statistically using t-tests. Results: The mean age of the sample was 25.0 yrs ± 8.7. The mean treatment time was 15.5 mths ± 5.2. Post-treatment, the transpalatal bone width increased from 35.3 mm ± 3.0 to 38.5 mm ± 2.0 (P < 0.001); the maxillary air sinus volume on the left side increased from 18.8 cm3 ± 6.5 to 20.0 cm3 ± 6.0 (P < 0.05), and from 18.5 cm3 ± 5.7 to 19.7 cm3 ± 5.8 (P < 0.05) on the right side. Conclusions: Biomimetic oral appliance therapy may be able to increase the maxillary air sinus volume in adults. In view of these preliminary findings, further studies on the effect of enhanced pneumatization on paranasal sinus function and sleep parameters are warranted.G. Dave SinghHee Nam KimKeAi Communications Co., Ltd.articlePneumatizationMaxillary air sinusBiomimeticOral appliance therapyPalatal expansionOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 7, Iss 2, Pp 133-138 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pneumatization Maxillary air sinus Biomimetic Oral appliance therapy Palatal expansion Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Pneumatization Maxillary air sinus Biomimetic Oral appliance therapy Palatal expansion Otorhinolaryngology RF1-547 Surgery RD1-811 G. Dave Singh Hee Nam Kim Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy
description	Objective: For the treatment of obstructive sleep apnea in adults, mandibular advancement devices (MADs) are often used. Since adults with a prognathic mandibular phenotype are at risk of developing an unfavorable facial profile, midfacial development using biomimetic oral appliance therapy might provide a suitable alternative. However, the effect of this procedure on the maxillary air sinuses is unknown; therefore, changes in sinus pneumatization were investigated in this study. Methods: After obtaining informed consent, 16 consecutive Korean adults with midfacial hypoplasia had 3D cone-beam (CB) CT scans taken, and biomimetic upper appliances (DNA appliance®, Vivos Therapeutics, Inc., USA) were constructed.All subjects were instructed to wear the device 12–16 h/day. Each month, examination for the progress of midfacial development was recorded. Post-treatment, a follow-up 3D CBCT scan was undertaken with no device in the patient's mouth. Pre- and post-treatment linear and volumetric measurements were obtained using appropriate software, and compared statistically using t-tests. Results: The mean age of the sample was 25.0 yrs ± 8.7. The mean treatment time was 15.5 mths ± 5.2. Post-treatment, the transpalatal bone width increased from 35.3 mm ± 3.0 to 38.5 mm ± 2.0 (P < 0.001); the maxillary air sinus volume on the left side increased from 18.8 cm3 ± 6.5 to 20.0 cm3 ± 6.0 (P < 0.05), and from 18.5 cm3 ± 5.7 to 19.7 cm3 ± 5.8 (P < 0.05) on the right side. Conclusions: Biomimetic oral appliance therapy may be able to increase the maxillary air sinus volume in adults. In view of these preliminary findings, further studies on the effect of enhanced pneumatization on paranasal sinus function and sleep parameters are warranted.
format	article
author	G. Dave Singh Hee Nam Kim
author_facet	G. Dave Singh Hee Nam Kim
author_sort	G. Dave Singh
title	Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy
title_short	Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy
title_full	Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy
title_fullStr	Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy
title_full_unstemmed	Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy
title_sort	changes in pneumatization of the maxillary air sinuses in korean adults following biomimetic oral appliance therapy
publisher	KeAi Communications Co., Ltd.
publishDate	2021
url	https://doaj.org/article/474c2e2558f14f2987d9a6f913d7dd5e
work_keys_str_mv	AT gdavesingh changesinpneumatizationofthemaxillaryairsinusesinkoreanadultsfollowingbiomimeticoralappliancetherapy AT heenamkim changesinpneumatizationofthemaxillaryairsinusesinkoreanadultsfollowingbiomimeticoralappliancetherapy
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Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy

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