HLH-11 modulates lipid metabolism in response to nutrient availability
Organismal metabolism fluctuates depending on nutritional conditions. Here, the authors show that, in C. elegans, HLH-11 negatively regulates lipid metabolism genes in the presence of nutrients and that its abundance decreased in response to starvation, thereby promoting fat utilization.
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2020
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/474e3a91eed844a582555d962edcc99b |
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| Sumario: | Organismal metabolism fluctuates depending on nutritional conditions. Here, the authors show that, in C. elegans, HLH-11 negatively regulates lipid metabolism genes in the presence of nutrients and that its abundance decreased in response to starvation, thereby promoting fat utilization. |
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