HLH-11 modulates lipid metabolism in response to nutrient availability

Organismal metabolism fluctuates depending on nutritional conditions. Here, the authors show that, in C. elegans, HLH-11 negatively regulates lipid metabolism genes in the presence of nutrients and that its abundance decreased in response to starvation, thereby promoting fat utilization.

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Detalles Bibliográficos
Autores principales:	Yi Li, Wanqiu Ding, Chuan-Yun Li, Ying Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/474e3a91eed844a582555d962edcc99b
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spelling	oai:doaj.org-article:474e3a91eed844a582555d962edcc99b2021-12-02T14:16:24ZHLH-11 modulates lipid metabolism in response to nutrient availability10.1038/s41467-020-19754-12041-1723https://doaj.org/article/474e3a91eed844a582555d962edcc99b2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19754-1https://doaj.org/toc/2041-1723Organismal metabolism fluctuates depending on nutritional conditions. Here, the authors show that, in C. elegans, HLH-11 negatively regulates lipid metabolism genes in the presence of nutrients and that its abundance decreased in response to starvation, thereby promoting fat utilization.Yi LiWanqiu DingChuan-Yun LiYing LiuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yi Li Wanqiu Ding Chuan-Yun Li Ying Liu HLH-11 modulates lipid metabolism in response to nutrient availability
description	Organismal metabolism fluctuates depending on nutritional conditions. Here, the authors show that, in C. elegans, HLH-11 negatively regulates lipid metabolism genes in the presence of nutrients and that its abundance decreased in response to starvation, thereby promoting fat utilization.
format	article
author	Yi Li Wanqiu Ding Chuan-Yun Li Ying Liu
author_facet	Yi Li Wanqiu Ding Chuan-Yun Li Ying Liu
author_sort	Yi Li
title	HLH-11 modulates lipid metabolism in response to nutrient availability
title_short	HLH-11 modulates lipid metabolism in response to nutrient availability
title_full	HLH-11 modulates lipid metabolism in response to nutrient availability
title_fullStr	HLH-11 modulates lipid metabolism in response to nutrient availability
title_full_unstemmed	HLH-11 modulates lipid metabolism in response to nutrient availability
title_sort	hlh-11 modulates lipid metabolism in response to nutrient availability
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/474e3a91eed844a582555d962edcc99b
work_keys_str_mv	AT yili hlh11modulateslipidmetabolisminresponsetonutrientavailability AT wanqiuding hlh11modulateslipidmetabolisminresponsetonutrientavailability AT chuanyunli hlh11modulateslipidmetabolisminresponsetonutrientavailability AT yingliu hlh11modulateslipidmetabolisminresponsetonutrientavailability
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HLH-11 modulates lipid metabolism in response to nutrient availability

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