CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis

The mechanistic details of fatty acid uptake into cells remains poorly understood. Here, the authors identify CD36 internalization via cavaeolae and demonstrate dynamic palmitoylationof CD36 is required for endocytic uptake of fatty acids.

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Autores principales:	Jian-Wei Hao, Juan Wang, Huiling Guo, Yin-Yue Zhao, Hui-Hui Sun, Yi-Fan Li, Xiao-Ying Lai, Ning Zhao, Xu Wang, Changchuan Xie, Lixin Hong, Xi Huang, Hong-Rui Wang, Cheng-Bin Li, Bin Liang, Shuai Chen, Tong-Jin Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/475bc3befce0421399240b3b2a58b6c8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:475bc3befce0421399240b3b2a58b6c82021-12-02T15:15:05ZCD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis10.1038/s41467-020-18565-82041-1723https://doaj.org/article/475bc3befce0421399240b3b2a58b6c82020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18565-8https://doaj.org/toc/2041-1723The mechanistic details of fatty acid uptake into cells remains poorly understood. Here, the authors identify CD36 internalization via cavaeolae and demonstrate dynamic palmitoylationof CD36 is required for endocytic uptake of fatty acids.Jian-Wei HaoJuan WangHuiling GuoYin-Yue ZhaoHui-Hui SunYi-Fan LiXiao-Ying LaiNing ZhaoXu WangChangchuan XieLixin HongXi HuangHong-Rui WangCheng-Bin LiBin LiangShuai ChenTong-Jin ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jian-Wei Hao Juan Wang Huiling Guo Yin-Yue Zhao Hui-Hui Sun Yi-Fan Li Xiao-Ying Lai Ning Zhao Xu Wang Changchuan Xie Lixin Hong Xi Huang Hong-Rui Wang Cheng-Bin Li Bin Liang Shuai Chen Tong-Jin Zhao CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
description	The mechanistic details of fatty acid uptake into cells remains poorly understood. Here, the authors identify CD36 internalization via cavaeolae and demonstrate dynamic palmitoylationof CD36 is required for endocytic uptake of fatty acids.
format	article
author	Jian-Wei Hao Juan Wang Huiling Guo Yin-Yue Zhao Hui-Hui Sun Yi-Fan Li Xiao-Ying Lai Ning Zhao Xu Wang Changchuan Xie Lixin Hong Xi Huang Hong-Rui Wang Cheng-Bin Li Bin Liang Shuai Chen Tong-Jin Zhao
author_facet	Jian-Wei Hao Juan Wang Huiling Guo Yin-Yue Zhao Hui-Hui Sun Yi-Fan Li Xiao-Ying Lai Ning Zhao Xu Wang Changchuan Xie Lixin Hong Xi Huang Hong-Rui Wang Cheng-Bin Li Bin Liang Shuai Chen Tong-Jin Zhao
author_sort	Jian-Wei Hao
title	CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
title_short	CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
title_full	CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
title_fullStr	CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
title_full_unstemmed	CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
title_sort	cd36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/475bc3befce0421399240b3b2a58b6c8
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CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis

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