Time to reconsider the role of ribavirin in Lassa fever.

Ribavirin is the only available Lassa fever treatment. The rationale for using ribavirin is based on one clinical study conducted in the early 1980s. However, reanalysis of previous unpublished data reveals that ribavirin may actually be harmful in some Lassa fever patients. An urgent reevaluation o...

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Autores principales:	Alex Paddy Salam, Vincent Cheng, Tansy Edwards, Piero Olliaro, Jonathan Sterne, Peter Horby
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/4763774884534bc790cd73d9a203fb9a
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spelling	oai:doaj.org-article:4763774884534bc790cd73d9a203fb9a2021-11-25T06:33:32ZTime to reconsider the role of ribavirin in Lassa fever.1935-27271935-273510.1371/journal.pntd.0009522https://doaj.org/article/4763774884534bc790cd73d9a203fb9a2021-07-01T00:00:00Zhttps://doi.org/10.1371/journal.pntd.0009522https://doaj.org/toc/1935-2727https://doaj.org/toc/1935-2735Ribavirin is the only available Lassa fever treatment. The rationale for using ribavirin is based on one clinical study conducted in the early 1980s. However, reanalysis of previous unpublished data reveals that ribavirin may actually be harmful in some Lassa fever patients. An urgent reevaluation of ribavirin is therefore needed.Alex Paddy SalamVincent ChengTansy EdwardsPiero OlliaroJonathan SternePeter HorbyPublic Library of Science (PLoS)articleArctic medicine. Tropical medicineRC955-962Public aspects of medicineRA1-1270ENPLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009522 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
spellingShingle	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Alex Paddy Salam Vincent Cheng Tansy Edwards Piero Olliaro Jonathan Sterne Peter Horby Time to reconsider the role of ribavirin in Lassa fever.
description	Ribavirin is the only available Lassa fever treatment. The rationale for using ribavirin is based on one clinical study conducted in the early 1980s. However, reanalysis of previous unpublished data reveals that ribavirin may actually be harmful in some Lassa fever patients. An urgent reevaluation of ribavirin is therefore needed.
format	article
author	Alex Paddy Salam Vincent Cheng Tansy Edwards Piero Olliaro Jonathan Sterne Peter Horby
author_facet	Alex Paddy Salam Vincent Cheng Tansy Edwards Piero Olliaro Jonathan Sterne Peter Horby
author_sort	Alex Paddy Salam
title	Time to reconsider the role of ribavirin in Lassa fever.
title_short	Time to reconsider the role of ribavirin in Lassa fever.
title_full	Time to reconsider the role of ribavirin in Lassa fever.
title_fullStr	Time to reconsider the role of ribavirin in Lassa fever.
title_full_unstemmed	Time to reconsider the role of ribavirin in Lassa fever.
title_sort	time to reconsider the role of ribavirin in lassa fever.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/4763774884534bc790cd73d9a203fb9a
work_keys_str_mv	AT alexpaddysalam timetoreconsidertheroleofribavirininlassafever AT vincentcheng timetoreconsidertheroleofribavirininlassafever AT tansyedwards timetoreconsidertheroleofribavirininlassafever AT pieroolliaro timetoreconsidertheroleofribavirininlassafever AT jonathansterne timetoreconsidertheroleofribavirininlassafever AT peterhorby timetoreconsidertheroleofribavirininlassafever
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Time to reconsider the role of ribavirin in Lassa fever.

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