Severe Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature

Background: Polymorphic eruption of pregnancy [PEP] is a benign inflammatory dermatosis of pregnancy of unknown etiology developing in the third trimester as an intensely pruritic rash and inflamed striae with peri-umbilical sparing. It is a self-limiting condition which resolves after delivery and...

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Autores principales:	Shashwati Sen, Harish Srivastava, Gautam Sen
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	polymorphic dermatosis pruritis peri-umbilical sparing pregnancy Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4765a1c26a094945b3250d7e077f1048
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spelling	oai:doaj.org-article:4765a1c26a094945b3250d7e077f10482021-12-02T13:52:45ZSevere Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature2636-41742682-378010.21608/ijma.2020.22209.1084https://doaj.org/article/4765a1c26a094945b3250d7e077f10482020-04-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_73206_b9c3bef45ab8f3346d241b6f25a55215.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Polymorphic eruption of pregnancy [PEP] is a benign inflammatory dermatosis of pregnancy of unknown etiology developing in the third trimester as an intensely pruritic rash and inflamed striae with peri-umbilical sparing. It is a self-limiting condition which resolves after delivery and has no maternal or fetal adverse effects. There are no specific investigations. Diagnosis is based on history and typical clinical features. Emollients, topical corticosteroids and oral antihistamines provide symptomatic relief, though a few patients with severe symptoms may require a short course of oral or injectable corticosteroids. Autologous hemotherapy is a safe option and can be considered in severe conditions. Case summary: This report describes an unusual patient with singleton pregnancy presenting at 41 weeks gestation with sudden onset intense itching and rash on abdomen, upper part of legs and arms. We have summarized current literature related to PEP and evaluated the variations in clinical presentations, relevant etiopathogenesis and treatment options.Shashwati SenHarish SrivastavaGautam SenAl-Azhar University, Faculty of Medicine (Damietta)articlepolymorphicdermatosispruritisperi-umbilical sparingpregnancyMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 2, Pp 328-331 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	polymorphic dermatosis pruritis peri-umbilical sparing pregnancy Medicine (General) R5-920
spellingShingle	polymorphic dermatosis pruritis peri-umbilical sparing pregnancy Medicine (General) R5-920 Shashwati Sen Harish Srivastava Gautam Sen Severe Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature
description	Background: Polymorphic eruption of pregnancy [PEP] is a benign inflammatory dermatosis of pregnancy of unknown etiology developing in the third trimester as an intensely pruritic rash and inflamed striae with peri-umbilical sparing. It is a self-limiting condition which resolves after delivery and has no maternal or fetal adverse effects. There are no specific investigations. Diagnosis is based on history and typical clinical features. Emollients, topical corticosteroids and oral antihistamines provide symptomatic relief, though a few patients with severe symptoms may require a short course of oral or injectable corticosteroids. Autologous hemotherapy is a safe option and can be considered in severe conditions. Case summary: This report describes an unusual patient with singleton pregnancy presenting at 41 weeks gestation with sudden onset intense itching and rash on abdomen, upper part of legs and arms. We have summarized current literature related to PEP and evaluated the variations in clinical presentations, relevant etiopathogenesis and treatment options.
format	article
author	Shashwati Sen Harish Srivastava Gautam Sen
author_facet	Shashwati Sen Harish Srivastava Gautam Sen
author_sort	Shashwati Sen
title	Severe Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature
title_short	Severe Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature
title_full	Severe Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature
title_fullStr	Severe Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature
title_full_unstemmed	Severe Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature
title_sort	severe polymorphic eruption of pregnancy developing in a late term primigravida: a case report and review of literature
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/4765a1c26a094945b3250d7e077f1048
work_keys_str_mv	AT shashwatisen severepolymorphiceruptionofpregnancydevelopinginalatetermprimigravidaacasereportandreviewofliterature AT harishsrivastava severepolymorphiceruptionofpregnancydevelopinginalatetermprimigravidaacasereportandreviewofliterature AT gautamsen severepolymorphiceruptionofpregnancydevelopinginalatetermprimigravidaacasereportandreviewofliterature
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Severe Polymorphic Eruption of Pregnancy Developing in A Late Term Primigravida: A Case Report and Review of Literature

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