Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review

Orthopedic implant failure is the most common complication of orthopedic surgery, causing serious trauma and resulting in a tremendous economic burden for patients. There are many reasons for implant failure, among which peri-implant infection (or implant-related infection) and aseptic loosening are...

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Autores principales:	Gang Tan, Jing Xu, Walter Munesu Chirume, Jieyu Zhang, Hui Zhang, Xuefeng Hu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	anti-inflammatory agents antibacterial agents coating nanoparticles orthopedic implants infection Engineering (General). Civil engineering (General) TA1-2040
Acceso en línea:	https://doaj.org/article/476a13646e294ef2a86018407c7ae81c
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id	oai:doaj.org-article:476a13646e294ef2a86018407c7ae81c
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spelling	oai:doaj.org-article:476a13646e294ef2a86018407c7ae81c2021-11-25T17:16:51ZAntibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review10.3390/coatings111114012079-6412https://doaj.org/article/476a13646e294ef2a86018407c7ae81c2021-11-01T00:00:00Zhttps://www.mdpi.com/2079-6412/11/11/1401https://doaj.org/toc/2079-6412Orthopedic implant failure is the most common complication of orthopedic surgery, causing serious trauma and resulting in a tremendous economic burden for patients. There are many reasons for implant failure, among which peri-implant infection (or implant-related infection) and aseptic loosening are the most important. At present, orthopedic doctors have many methods to treat these complications, such as revision surgery, which have shown good results. However, if peri-implant infection can be prevented, this will bring about significant social benefits. Many studies have focused on adding antibacterial substances to the implant coating, and with a deeper understanding of the mechanism of implant failure, adding such substances by different modification methods has become a research hot spot. This review aims to summarize the antibacterial and anti-inflammatory substances that can be used as coating materials in orthopedic implants and to provide a reference for the prevention and treatment of implant failure caused by implant-related infection and excessive inflammation.Gang TanJing XuWalter Munesu ChirumeJieyu ZhangHui ZhangXuefeng HuMDPI AGarticleanti-inflammatory agentsantibacterial agentscoatingnanoparticlesorthopedic implantsinfectionEngineering (General). Civil engineering (General)TA1-2040ENCoatings, Vol 11, Iss 1401, p 1401 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	anti-inflammatory agents antibacterial agents coating nanoparticles orthopedic implants infection Engineering (General). Civil engineering (General) TA1-2040
spellingShingle	anti-inflammatory agents antibacterial agents coating nanoparticles orthopedic implants infection Engineering (General). Civil engineering (General) TA1-2040 Gang Tan Jing Xu Walter Munesu Chirume Jieyu Zhang Hui Zhang Xuefeng Hu Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review
description	Orthopedic implant failure is the most common complication of orthopedic surgery, causing serious trauma and resulting in a tremendous economic burden for patients. There are many reasons for implant failure, among which peri-implant infection (or implant-related infection) and aseptic loosening are the most important. At present, orthopedic doctors have many methods to treat these complications, such as revision surgery, which have shown good results. However, if peri-implant infection can be prevented, this will bring about significant social benefits. Many studies have focused on adding antibacterial substances to the implant coating, and with a deeper understanding of the mechanism of implant failure, adding such substances by different modification methods has become a research hot spot. This review aims to summarize the antibacterial and anti-inflammatory substances that can be used as coating materials in orthopedic implants and to provide a reference for the prevention and treatment of implant failure caused by implant-related infection and excessive inflammation.
format	article
author	Gang Tan Jing Xu Walter Munesu Chirume Jieyu Zhang Hui Zhang Xuefeng Hu
author_facet	Gang Tan Jing Xu Walter Munesu Chirume Jieyu Zhang Hui Zhang Xuefeng Hu
author_sort	Gang Tan
title	Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review
title_short	Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review
title_full	Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review
title_fullStr	Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review
title_full_unstemmed	Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review
title_sort	antibacterial and anti-inflammatory coating materials for orthopedic implants: a review
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/476a13646e294ef2a86018407c7ae81c
work_keys_str_mv	AT gangtan antibacterialandantiinflammatorycoatingmaterialsfororthopedicimplantsareview AT jingxu antibacterialandantiinflammatorycoatingmaterialsfororthopedicimplantsareview AT waltermunesuchirume antibacterialandantiinflammatorycoatingmaterialsfororthopedicimplantsareview AT jieyuzhang antibacterialandantiinflammatorycoatingmaterialsfororthopedicimplantsareview AT huizhang antibacterialandantiinflammatorycoatingmaterialsfororthopedicimplantsareview AT xuefenghu antibacterialandantiinflammatorycoatingmaterialsfororthopedicimplantsareview
_version_	1718412526055587840

Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review

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