Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure

Abstract To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted p...

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Autores principales:	Lawrence Chun Man Lau, Wayne Yuk Wai Lee, Anthony P. H. Butler, Alex I. Chernoglazov, Kwong Yin Chung, Kevin Ki Wai Ho, James Griffith, Philip H. Butler, Patrick Shu Hang Yung
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/476c011bac2a45c0b988bebefaa61a7d
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spelling	oai:doaj.org-article:476c011bac2a45c0b988bebefaa61a7d2021-12-02T15:23:06ZMulti-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure10.1038/s41598-020-80463-22045-2322https://doaj.org/article/476c011bac2a45c0b988bebefaa61a7d2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80463-2https://doaj.org/toc/2045-2322Abstract To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis [NexGen Legacy Posterior Stabilized (LPS) TKA] was analyzed as were pre-operative imaging examination and compared with a MARS-CT examination obtained of the extracted TKA prosthesis. Radiographs, fluoroscopy, ultrasound and MRI preoperatively did not reveal the cause of the implant failure. MARS CT images of the extracted prosthesis clearly showed the presence of posteromedial polyethylene and tibial tray wear which is compatible with the clinical appearance of the extracted TKA. MARS can identify polyethylene insert and metallic tibial tray wear as a cause of TKA failure, that could not be identified with on standard pre-operative imaging. Although clinical MARS CT system is still under development, this case does illustrate its potential clinical usefulness. This is the first study to document how MARS CT imaging can detect orthopedic implant failure not detected by standard current imaging techniques. This system has a potential clinical application in orthopedic patients.Lawrence Chun Man LauWayne Yuk Wai LeeAnthony P. H. ButlerAlex I. ChernoglazovKwong Yin ChungKevin Ki Wai HoJames GriffithPhilip H. ButlerPatrick Shu Hang YungNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lawrence Chun Man Lau Wayne Yuk Wai Lee Anthony P. H. Butler Alex I. Chernoglazov Kwong Yin Chung Kevin Ki Wai Ho James Griffith Philip H. Butler Patrick Shu Hang Yung Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
description	Abstract To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis [NexGen Legacy Posterior Stabilized (LPS) TKA] was analyzed as were pre-operative imaging examination and compared with a MARS-CT examination obtained of the extracted TKA prosthesis. Radiographs, fluoroscopy, ultrasound and MRI preoperatively did not reveal the cause of the implant failure. MARS CT images of the extracted prosthesis clearly showed the presence of posteromedial polyethylene and tibial tray wear which is compatible with the clinical appearance of the extracted TKA. MARS can identify polyethylene insert and metallic tibial tray wear as a cause of TKA failure, that could not be identified with on standard pre-operative imaging. Although clinical MARS CT system is still under development, this case does illustrate its potential clinical usefulness. This is the first study to document how MARS CT imaging can detect orthopedic implant failure not detected by standard current imaging techniques. This system has a potential clinical application in orthopedic patients.
format	article
author	Lawrence Chun Man Lau Wayne Yuk Wai Lee Anthony P. H. Butler Alex I. Chernoglazov Kwong Yin Chung Kevin Ki Wai Ho James Griffith Philip H. Butler Patrick Shu Hang Yung
author_facet	Lawrence Chun Man Lau Wayne Yuk Wai Lee Anthony P. H. Butler Alex I. Chernoglazov Kwong Yin Chung Kevin Ki Wai Ho James Griffith Philip H. Butler Patrick Shu Hang Yung
author_sort	Lawrence Chun Man Lau
title	Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_short	Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_full	Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_fullStr	Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_full_unstemmed	Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_sort	multi-energy spectral photon-counting computed tomography (mars) for detection of arthroplasty implant failure
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/476c011bac2a45c0b988bebefaa61a7d
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Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure

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