Single-cell analysis reveals early manifestation of cancerous phenotype in pre-malignant esophageal cells.

Cellular heterogeneity plays a pivotal role in a variety of functional processes in vivo including carcinogenesis. However, our knowledge about cell-to-cell diversity and how differences in individual cells manifest in alterations at the population level remains very limited mainly due to the lack o...

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Autores principales: Jiangxin Wang, Xu Shi, Roger H Johnson, Laimonas Kelbauskas, Weiwen Zhang, Deirdre R Meldrum
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/476dc4e1f2cc428494d89b53d1668589
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