Deletion of running-induced hippocampal neurogenesis by irradiation prevents development of an anxious phenotype in mice.

Recent evidence postulates a role of hippocampal neurogenesis in anxiety behavior. Here we report that elevated levels of neurogenesis elicit increased anxiety in rodents. Mice performing voluntary wheel running displayed both highly elevated levels of neurogenesis and increased anxiety in three dif...

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Autores principales: Johannes Fuss, Nada M B Ben Abdallah, Frank W Hensley, Klaus-Josef Weber, Rainer Hellweg, Peter Gass
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/4796f8c949744c619fe75fe430fefdc1
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