A cell-based computational modeling approach for developing site-directed molecular probes.

Modeling the local absorption and retention patterns of membrane-permeant small molecules in a cellular context could facilitate development of site-directed chemical agents for bioimaging or therapeutic applications. Here, we present an integrative approach to this problem, combining in silico comp...

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Autores principales: Jing-Yu Yu, Nan Zheng, Gerta Mane, Kyoung Ah Min, Juan P Hinestroza, Huaning Zhu, Kathleen A Stringer, Gus R Rosania
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/479eaf9397424fa08218a3a44784a9e1
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