A cell-based computational modeling approach for developing site-directed molecular probes.
Modeling the local absorption and retention patterns of membrane-permeant small molecules in a cellular context could facilitate development of site-directed chemical agents for bioimaging or therapeutic applications. Here, we present an integrative approach to this problem, combining in silico comp...
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Autores principales: | Jing-Yu Yu, Nan Zheng, Gerta Mane, Kyoung Ah Min, Juan P Hinestroza, Huaning Zhu, Kathleen A Stringer, Gus R Rosania |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/479eaf9397424fa08218a3a44784a9e1 |
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