A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
Purpose: To assess the outcomes of implanting a new polymethylmethacrylate (PMMA) ring (Neoring; AJL Ophthalmic) in pre-descemet deep anterior lamellar keratoplasty (PD-DALK) procedure for moderate-advanced keratoconus.Methods: This prospective study included 10 eyes of 10 patients with moderate-adv...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/47a621462e124879a8d77d09ac25baab |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:47a621462e124879a8d77d09ac25baab |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:47a621462e124879a8d77d09ac25baab2021-11-04T06:36:57ZA New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study2296-858X10.3389/fmed.2021.771365https://doaj.org/article/47a621462e124879a8d77d09ac25baab2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.771365/fullhttps://doaj.org/toc/2296-858XPurpose: To assess the outcomes of implanting a new polymethylmethacrylate (PMMA) ring (Neoring; AJL Ophthalmic) in pre-descemet deep anterior lamellar keratoplasty (PD-DALK) procedure for moderate-advanced keratoconus.Methods: This prospective study included 10 eyes of 10 patients with moderate-advanced keratoconus who underwent PD-DALK with Neoring implantation. Neoring was implanted in a pre-descemetic pocket. The post-operative examination included refraction, corrected distance visual acuity (CDVA), corneal tomography, and endothelial cell density (ECD). The root mean squares (RMSs) for coma-like aberrations and spherical aberration were evaluated for a pupil size of 4.5 mm. The junctional graft (Tg) and host (Th) thicknesses were measured. The post-operative follow-up was 24 months.Results: Post-operative CDVA was 0.82 ± 0.14 (decimal scale), 100% of the eyes achieved a CDVA of 0.7 (decimal scale). The refractive cylinder was −2.86 ± 1.65 2-years after surgery. No eyes had a post-operative refractive cylinder ≥5.00 D and in five eyes (50%), it was ≤2.50 D. At the last visit, the mean keratometry was 45.64 ± 1.96 D, the RMS for coma-like aberrations was 0.30 ± 0.15 μm and spherical aberration was 0.22 ± 0.09. The mean ECD remains without changes over the follow-up (P = 0.07). At the last visit, Tg and Th were 679.9 ± 39.0 and 634.8 ± 41.2 μm, respectively. The thickness of the complex (host-Neoring) was 740.6 ± 35.6 μm. In all cases, this thickness was thicker than Tg.Conclusion: The results of this study suggest that PD-DALK along Neoring implantation is a viable, effective, and safe option to optimize the post-operative results for moderate-severe keratoconus.Belén Alfonso-BartolozziCarlos LisaLuis Fernández-Vega-CuetoDavid Madrid-CostaJosé F. AlfonsoFrontiers Media S.A.articlecorneal transplantdeep anterior lamellar keratoplasty (DALK)visual outcomesrefractive outcomeskeratoconusMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
corneal transplant deep anterior lamellar keratoplasty (DALK) visual outcomes refractive outcomes keratoconus Medicine (General) R5-920 |
| spellingShingle |
corneal transplant deep anterior lamellar keratoplasty (DALK) visual outcomes refractive outcomes keratoconus Medicine (General) R5-920 Belén Alfonso-Bartolozzi Carlos Lisa Luis Fernández-Vega-Cueto David Madrid-Costa José F. Alfonso A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study |
| description |
Purpose: To assess the outcomes of implanting a new polymethylmethacrylate (PMMA) ring (Neoring; AJL Ophthalmic) in pre-descemet deep anterior lamellar keratoplasty (PD-DALK) procedure for moderate-advanced keratoconus.Methods: This prospective study included 10 eyes of 10 patients with moderate-advanced keratoconus who underwent PD-DALK with Neoring implantation. Neoring was implanted in a pre-descemetic pocket. The post-operative examination included refraction, corrected distance visual acuity (CDVA), corneal tomography, and endothelial cell density (ECD). The root mean squares (RMSs) for coma-like aberrations and spherical aberration were evaluated for a pupil size of 4.5 mm. The junctional graft (Tg) and host (Th) thicknesses were measured. The post-operative follow-up was 24 months.Results: Post-operative CDVA was 0.82 ± 0.14 (decimal scale), 100% of the eyes achieved a CDVA of 0.7 (decimal scale). The refractive cylinder was −2.86 ± 1.65 2-years after surgery. No eyes had a post-operative refractive cylinder ≥5.00 D and in five eyes (50%), it was ≤2.50 D. At the last visit, the mean keratometry was 45.64 ± 1.96 D, the RMS for coma-like aberrations was 0.30 ± 0.15 μm and spherical aberration was 0.22 ± 0.09. The mean ECD remains without changes over the follow-up (P = 0.07). At the last visit, Tg and Th were 679.9 ± 39.0 and 634.8 ± 41.2 μm, respectively. The thickness of the complex (host-Neoring) was 740.6 ± 35.6 μm. In all cases, this thickness was thicker than Tg.Conclusion: The results of this study suggest that PD-DALK along Neoring implantation is a viable, effective, and safe option to optimize the post-operative results for moderate-severe keratoconus. |
| format |
article |
| author |
Belén Alfonso-Bartolozzi Carlos Lisa Luis Fernández-Vega-Cueto David Madrid-Costa José F. Alfonso |
| author_facet |
Belén Alfonso-Bartolozzi Carlos Lisa Luis Fernández-Vega-Cueto David Madrid-Costa José F. Alfonso |
| author_sort |
Belén Alfonso-Bartolozzi |
| title |
A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study |
| title_short |
A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study |
| title_full |
A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study |
| title_fullStr |
A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study |
| title_full_unstemmed |
A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study |
| title_sort |
new pre-descemetic corneal ring (neoring) in deep anterior lamellar keratoplasty for moderate-advanced keratoconus: a pilot 2-year long-term follow-up study |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/47a621462e124879a8d77d09ac25baab |
| work_keys_str_mv |
AT belenalfonsobartolozzi anewpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT carloslisa anewpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT luisfernandezvegacueto anewpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT davidmadridcosta anewpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT josefalfonso anewpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT belenalfonsobartolozzi newpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT carloslisa newpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT luisfernandezvegacueto newpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT davidmadridcosta newpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy AT josefalfonso newpredescemeticcornealringneoringindeepanteriorlamellarkeratoplastyformoderateadvancedkeratoconusapilot2yearlongtermfollowupstudy |
| _version_ |
1718445084263841792 |