CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION

Objective: To assess the frequency of preoperative leukocytosis and its association with wound infection. Study Design: Prospective-cross sectional, analytical study. Place and Duration of Study: Department of Gynecology and Obstetrics, Combined Military Hospital, Thall, from Jan to Dec 2017....

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Autores principales:	Sadia Zainab, Amina Akbar, Saira Mahboob, Mobeen Ikram
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	preoperative leukocytosis postoperative wound infection sensitivity specificity Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/47a776abfd2f443a8e6aff35c5abab5f
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spelling	oai:doaj.org-article:47a776abfd2f443a8e6aff35c5abab5f2021-12-02T17:20:37ZCORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION0030-96482411-8842https://doaj.org/article/47a776abfd2f443a8e6aff35c5abab5f2020-10-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5581https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess the frequency of preoperative leukocytosis and its association with wound infection. Study Design: Prospective-cross sectional, analytical study. Place and Duration of Study: Department of Gynecology and Obstetrics, Combined Military Hospital, Thall, from Jan to Dec 2017. Methodology: After the approval of hospital ethics committee, 340 pregnant ladies undergoing both elective and emergency cesarean section were included in our study. The outcome of our study was the frequency of preoperative leukocytosis and its association with postoperative wound infection. SPSS version 20 was used to analyze data. The qualitative data was presented as frequency and percentage. Chi-square was used to analyze significance. A p-value ≤0.05 was taken as significant. Results: Frequency of preoperative leukocytosis was 121 (36.6%). A total of 111 (64.1%) pregnant ladies had pre-operative leukocytosis without post-operative wound infection versus 10 (66.6%) in patients with wound infection, p≤0.05, odd ratio 3.77. The sensitivity of pre-op total leukocyte count (TLC) for prediction of post-op wound infection was 66.6% (95% CI 38.3 to 88.8%) and specificity of 65.1% (59.5% to 70.34%). Most patients, 13 (86.6%), with wound infection required only debridement and intravenous antibiotics: IV linezolid and metronidazole; rest 2(13.4%) required secondary suturing for patient recovery. Conclusion: Preoperative leukocytosis was common in parturient undergoing cesarean section incidence of wound infection was low in this study. The post-operative wound infection risk is shown to correlate with the preoperative leukocytosis.Sadia ZainabAmina AkbarSaira MahboobMobeen IkramArmy Medical College Rawalpindiarticlepreoperative leukocytosispostoperative wound infectionsensitivityspecificityMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1439-1442 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	preoperative leukocytosis postoperative wound infection sensitivity specificity Medicine R Medicine (General) R5-920
spellingShingle	preoperative leukocytosis postoperative wound infection sensitivity specificity Medicine R Medicine (General) R5-920 Sadia Zainab Amina Akbar Saira Mahboob Mobeen Ikram CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION
description	Objective: To assess the frequency of preoperative leukocytosis and its association with wound infection. Study Design: Prospective-cross sectional, analytical study. Place and Duration of Study: Department of Gynecology and Obstetrics, Combined Military Hospital, Thall, from Jan to Dec 2017. Methodology: After the approval of hospital ethics committee, 340 pregnant ladies undergoing both elective and emergency cesarean section were included in our study. The outcome of our study was the frequency of preoperative leukocytosis and its association with postoperative wound infection. SPSS version 20 was used to analyze data. The qualitative data was presented as frequency and percentage. Chi-square was used to analyze significance. A p-value ≤0.05 was taken as significant. Results: Frequency of preoperative leukocytosis was 121 (36.6%). A total of 111 (64.1%) pregnant ladies had pre-operative leukocytosis without post-operative wound infection versus 10 (66.6%) in patients with wound infection, p≤0.05, odd ratio 3.77. The sensitivity of pre-op total leukocyte count (TLC) for prediction of post-op wound infection was 66.6% (95% CI 38.3 to 88.8%) and specificity of 65.1% (59.5% to 70.34%). Most patients, 13 (86.6%), with wound infection required only debridement and intravenous antibiotics: IV linezolid and metronidazole; rest 2(13.4%) required secondary suturing for patient recovery. Conclusion: Preoperative leukocytosis was common in parturient undergoing cesarean section incidence of wound infection was low in this study. The post-operative wound infection risk is shown to correlate with the preoperative leukocytosis.
format	article
author	Sadia Zainab Amina Akbar Saira Mahboob Mobeen Ikram
author_facet	Sadia Zainab Amina Akbar Saira Mahboob Mobeen Ikram
author_sort	Sadia Zainab
title	CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION
title_short	CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION
title_full	CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION
title_fullStr	CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION
title_full_unstemmed	CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION
title_sort	correlation of pre-operative leukocytosis with post-operative wound infection in caesarean-section
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/47a776abfd2f443a8e6aff35c5abab5f
work_keys_str_mv	AT sadiazainab correlationofpreoperativeleukocytosiswithpostoperativewoundinfectionincaesareansection AT aminaakbar correlationofpreoperativeleukocytosiswithpostoperativewoundinfectionincaesareansection AT sairamahboob correlationofpreoperativeleukocytosiswithpostoperativewoundinfectionincaesareansection AT mobeenikram correlationofpreoperativeleukocytosiswithpostoperativewoundinfectionincaesareansection
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CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION

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